Non-stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll-like receptor 4 (TLR4)

Although activated spinal cord glia contribute importantly to neuropathic pain, how nerve injury activates glia remains controversial. It has recently been proposed, on the basis of genetic approaches, that toll-like receptor 4 (TLR4) may be a key receptor for initiating microglial activation follow...

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Detalhes bibliográficos
Main Authors: Hutchinson, Mark R., Zhang, Yingning, Brown, Kimberley, Coats, Benjamen D., Shridhar, Mitesh, Sholar, Paige W., Patel, Sonica J., Crysdale, Nicole Y., Harrison, Jacqueline A., Maier, Steven F., Rice, Kenner C., Watkins, Linda R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2588470/
https://ncbi.nlm.nih.gov/pubmed/18662331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2008.06321.x
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