Synthetic Immunology: Hacking Immune Cells to Expand Their Therapeutic Capabilities

od Roybal, Kole T., Lim, Wendell A.
Izdano u Annu Rev Immunol (2017)

Tentative and transient natural killer cell polarization balances the requirements for discriminatory recognition and cytolytic efficacy

od Sinai, Parisa, Roybal, Kole T, Wülfing, Christoph
Izdano 2010

Synthetic Biology Approaches to Engineer T cells

od Wu, Chia-Yung, Rupp, Levi J., Roybal, Kole T., Lim, Wendell A.
Izdano u Curr Opin Immunol (2015)

Differential Regulation of the Period Genes in Striatal Regions following Cocaine Exposure

od Falcon, Edgardo, Ozburn, Angela, Mukherjee, Shibani, Roybal, Kole, McClung, Colleen A.
Izdano 2013

Remote control of therapeutic T cells through a small molecule-gated chimeric receptor

od Wu, Chia-Yung, Roybal, Kole T., Puchner, Elias M., Onuffer, James, Lim, Wendell A.
Izdano u Science (2015)

Early Signaling in Primary T Cells Activated by Antigen Presenting Cells Is Associated with a Deep and Transient Lamellal Actin Network

od Roybal, Kole T., Mace, Emily M., Mantell, Judith M., Verkade, Paul, Orange, Jordan S., Wülfing, Christoph
Izdano u PLoS One (2015)

IFN-α suppresses GATA3 transcription from a distal exon and promotes H3K27 tri-methylation of the CNS-1 enhancer in human Th2 cells()

od Huber, Jonathan P., Gonzales-van Horn, Sarah R., Roybal, Kole T., Gill, Michelle A., Farrar, J. David
Izdano 2014

IMMU-57. SEQUENTIAL TWO-RECEPTOR PRIMING CAR SYSTEM TO OVERCOME HETEROGENEOUS ANTIGEN EXPRESSION

od Watchmaker, Payal, Choe, Joseph, Carrera, Diego, Downey, Kira, Shahin, Maryam, Roybal, Kole, Lim, Wendell, Okada, Hideho
Izdano u Neuro Oncol (2018)

Engineering Customized Cell Sensing and Response Behaviors Using Synthetic Notch Receptors

od Morsut, Leonardo, Roybal, Kole T., Xiong, Xin, Gordley, Russell M., Coyle, Scott M., Thomson, Matthew, Lim, Wendell A.
Izdano u Cell (2016)

CRISPR/Cas9-mediated PD-1 disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells

od Rupp, Levi J., Schumann, Kathrin, Roybal, Kole T., Gate, Rachel E., Ye, Chun J., Lim, Wendell A., Marson, Alexander
Izdano u Sci Rep (2017)

IMMU-21. SEQUENTIAL TWO-RECEPTOR PRIMING CAR SYSTEM TO OVERCOME HETEROGENEOUS ANTIGEN EXPRESSION

od Watchmaker, Payal, Choe, Joseph, Carrera, Diego, Gilbert, Ryan, Yu, Wei, Downey, Kira, Roybal, Kole, Lim, Wendell, Okada, Hideho
Izdano u Neuro Oncol (2019)

Spatiotemporal Patterning During T Cell Activation Is Highly Diverse

od Singleton, Kentner L., Roybal, Kole T., Sun, Yi, Fu, Guo, Gascoigne, Nicholas R. J., van Oers, Nicolai S. C., Wülfing, Christoph
Izdano 2009

Modest Interference with Actin Dynamics in Primary T Cell Activation by Antigen Presenting Cells Preferentially Affects Lamellal Signaling

od Roybal, Kole T., Mace, Emily M., Clark, Danielle J., Leard, Alan D., Herman, Andrew, Verkade, Paul, Orange, Jordan S., Wülfing, Christoph
Izdano u PLoS One (2015)

Precision Tumor Recognition by T Cells With Combinatorial Antigen Sensing Circuits

od Roybal, Kole T., Rupp, Levi J., Morsut, Leonardo, Walker, Whitney J., McNally, Krista A., Park, Jason S., Lim, Wendell A.
Izdano u Cell (2016)

convertibleCARs: A chimeric antigen receptor system for flexible control of activity and antigen targeting

od Landgraf, Kyle E., Williams, Steven R., Steiger, Daniel, Gebhart, Dana, Lok, Stephen, Martin, David W., Roybal, Kole T., Kim, Kaman Chan
Izdano u Commun Biol (2020)

Enhancement of anti-tumor CD8 immunity by IgG1-mediated targeting of Fc receptors

od Furlan, Scott N, Mandraju, Rajakumar, Brewer, Travis, Roybal, Kole, Troutman, Ty Dale, Hu, Wei, Palm, Noah W, Unni, Arun, Pasare, Chandrashekhar
Izdano 2014

Mycobacterial Shuttle Vectors Designed for High-Level Protein Expression in Infected Macrophages

od Eitson, Jennifer L., Medeiros, Jennifer J., Hoover, Ashley R., Srivastava, Shashikant, Roybal, Kole T., Aínsa, José A., Hansen, Eric J., Gumbo, Tawanda, van Oers, Nicolai S. C.
Izdano 2012

Engineering T cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors

od Roybal, Kole T., Williams, Jasper Z., Morsut, Leonardo, Rupp, Levi J., Kolinko, Isabel, Choe, Joseph H., Walker, Whitney J., McNally, Krista A., Lim, Wendell A.
Izdano u Cell (2016)

Computational spatiotemporal analysis identifies WAVE2 and Cofilin as joint regulators of costimulation-mediated T cell actin dynamics

od Roybal, Kole T., Buck, Taráz E., Ruan, Xiongtao, Cho, Baek Hwan, Clark, Danielle J., Ambler, Rachel, Tunbridge, Helen M., Zhang, Jianwei, Verkade, Paul, Wülfing, Christoph, Murphy, Robert F.
Izdano u Sci Signal (2016)

The CD3 ζ subunit contains a phosphoinositide-binding motif that is required for the stable accumulation of TCR/CD3 complex at the immunological synapse

od DeFord-Watts, Laura M., Dougall, David S., Belkaya, Serkan, Johnson, Blake A., Eitson, Jennifer L., Roybal, Kole T., Barylko, Barbara, Albanesi, Joseph P., Wülfing, Christoph, van Oers, Nicolai S.C.
Izdano 2011