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Engineering T cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors
Redirecting T cells to attack cancer using engineered chimeric receptors provides powerful new therapeutic capabilities. But the effectiveness of therapeutic T cells is constrained by the endogenous T cell response: certain facets of natural response programs can be toxic, whereas other responses, s...
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| Publicat a: | Cell |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5072533/ https://ncbi.nlm.nih.gov/pubmed/27693353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.09.011 |
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