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Engineering T cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors
Redirecting T cells to attack cancer using engineered chimeric receptors provides powerful new therapeutic capabilities. But the effectiveness of therapeutic T cells is constrained by the endogenous T cell response: certain facets of natural response programs can be toxic, whereas other responses, s...
שמור ב:
| הוצא לאור ב: | Cell |
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| Main Authors: | , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5072533/ https://ncbi.nlm.nih.gov/pubmed/27693353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.09.011 |
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