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Precision Tumor Recognition by T Cells With Combinatorial Antigen Sensing Circuits
T cells can be re-directed to kill cancer cells using chimeric antigen receptors (CARs) or T cell receptors (TCRs). This approach, however, is constrained by the rarity of tumor-specific single antigens. Targeting antigens also found on bystander tissues can cause life-threatening adverse effects. A...
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| Publicado no: | Cell |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4752902/ https://ncbi.nlm.nih.gov/pubmed/26830879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.01.011 |
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