טוען...
Discriminatory Power of Combinatorial Antigen Recognition in Cancer T Cell Therapies
Precise discrimination of tumor from normal tissues remains a major roadblock for therapeutic efficacy of chimeric antigen receptor (CAR) T cells. Here, we perform a comprehensive in silico screen to identify multi-antigen signatures that improve tumor discrimination by CAR T cells engineered to int...
שמור ב:
| הוצא לאור ב: | Cell Syst |
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| Main Authors: | , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7814417/ https://ncbi.nlm.nih.gov/pubmed/32916097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2020.08.002 |
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