Interferon Control of the Sterol Metabolic Network: Bidirectional Molecular Circuitry-Mediating Host Protection

por Robertson, Kevin A., Ghazal, Peter
Publicado en Front Immunol (2016)

Regression of a Murine Gammaherpesvirus 68-Positive B-Cell Lymphoma Mediated by CD4 T Lymphocytes

por Robertson, Kevin A., Usherwood, Edward J., Nash, Anthony A.
Publicado 2001

Metabolic Regulators Nampt and Sirt6 Serially Participate in the Macrophage Interferon Antiviral Cascade

por Dantoft, Widad, Robertson, Kevin A., Watkins, W. John, Strobl, Birgit, Ghazal, Peter
Publicado en Front Microbiol (2019)

Discrete Clusters of Virus-Encoded MicroRNAs Are Associated with Complementary Strands of the Genome and the 7.2-Kilobase Stable Intron in Murine Cytomegalovirus

por Buck, Amy H., Santoyo-Lopez, Javier, Robertson, Kevin A., Kumar, Diwakar S., Reczko, Martin, Ghazal, Peter
Publicado 2007

Rapid proteasomal elimination of 3-hydroxy-3-methylglutaryl-CoA reductase by interferon- [Formula: see text] in primary macrophages requires endogenous 25-hydroxycholesterol synthe...

por Lu, Hongjin, Talbot, Simon, Robertson, Kevin A., Watterson, Steven, Forster, Thorsten, Roy, Douglas, Ghazal, Peter
Publicado en Steroids (2015)

A logic-based diagram of signalling pathways central to macrophage activation

por Raza, Sobia, Robertson, Kevin A, Lacaze, Paul A, Page, David, Enright, Anton J, Ghazal, Peter, Freeman, Tom C
Publicado 2008

Expression Profiling Reveals Novel Innate and Inflammatory Responses in the Jejunal Epithelial Compartment during Infection with Trichinella spiralis

por Knight, Pamela A., Pemberton, Alan D., Robertson, Kevin A., Roy, Douglas J., Wright, Steven H., Miller, Hugh R. P.
Publicado 2004

Training Multidisciplinary Biomedical Informatics Students: Three Years of Experience

por van Mulligen, Erik M., Cases, Montserrat, Hettne, Kristina, Molero, Eva, Weeber, Marc, Robertson, Kevin A., Oliva, Baldomero, de la Calle, Guillermo, Maojo, Victor
Publicado 2008

Differential proteomics analysis of synaptic proteins identifies potential cellular targets and protein mediators of synaptic neuroprotection conferred by the slow Wallerian degene...

por Wishart, Thomas M., Paterson, Janet M., Short, Duncan M., Meredith, Sara, Robertson, Kevin A., Sutherland, Calum, Cousin, Michael A., Dutia, Mayank B., Gillingwater, Thomas H.
Publicado 2007

A model of flux regulation in the cholesterol biosynthesis pathway: Immune mediated graduated flux reduction versus statin-like led stepped flux reduction

por Watterson, Steven, Guerriero, Maria Luisa, Blanc, Mathieu, Mazein, Alexander, Loewe, Laurence, Robertson, Kevin A., Gibbs, Holly, Shui, Guanghou, Wenk, Markus R., Hillston, Jane, Ghazal, Peter
Publicado 2013

Chronic Mild Hypoxia Protects Heart-derived H9c2 Cells against Acute Hypoxia/Reoxygenation by Regulating Expression of the SUR2A Subunit of the ATP-sensitive K(+) Channel

por Crawford, Russell M., Jovanović, Sofija, Budas, Grant R., Davies, Anthony M., Lad, Harish, Wenger, Roland H., Robertson, Kevin A., Roy, Douglas J., Ranki, Harri J., Jovanović, Aleksandar
Publicado 2003

GPX-Macrophage Expression Atlas: A database for expression profiles of macrophages challenged with a variety of pro-inflammatory, anti-inflammatory, benign and pathogen insults

por Grimes, Graeme R, Moodie, Stuart, Beattie, John S, Craigon, Marie, Dickinson, Paul, Forster, Thorsten, Livingston, Andrew D, Mewissen, Muriel, Robertson, Kevin A, Ross, Alan J, Sing, Garwin, Ghazal, Peter
Publicado 2005

Reversible Inhibition of Murine Cytomegalovirus Replication by Gamma Interferon (IFN-γ) in Primary Macrophages Involves a Primed Type I IFN-Signaling Subnetwork for Full Establishm...

por Kropp, Kai A., Robertson, Kevin A., Sing, Garwin, Rodriguez-Martin, Sara, Blanc, Mathieu, Lacaze, Paul, Hassim, Muhamad F. B. Noor, Khondoker, Mizanur R., Busche, Andreas, Dickinson, Paul, Forster, Thorsten, Strobl, Birgit, Mueller, Mathias, Jonjic, Stipan, Angulo, Ana, Ghazal, Peter
Publicado 2011

Host Defense against Viral Infection Involves Interferon Mediated Down-Regulation of Sterol Biosynthesis

por Blanc, Mathieu, Hsieh, Wei Yuan, Robertson, Kevin A., Watterson, Steven, Shui, Guanghou, Lacaze, Paul, Khondoker, Mizanur, Dickinson, Paul, Sing, Garwin, Rodríguez-Martín, Sara, Phelan, Peter, Forster, Thorsten, Strobl, Birgit, Müller, Matthias, Riemersma, Rudolph, Osborne, Timothy, Wenk, Markus R., Angulo, Ana, Ghazal, Peter
Publicado 2011

The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells

por Perucha, Esperanza, Melchiotti, Rossella, Bibby, Jack A, Wu, Wing, Frederiksen, Klaus Stensgaard, Roberts, Ceri A., Hall, Zoe, LeFriec, Gaelle, Robertson, Kevin A., Lavender, Paul, Gerwien, Jens Gammeltoft, Taams, Leonie S., Griffin, Julian L., de Rinaldis, Emanuele, van Baarsen, Lisa G. M., Kemper, Claudia, Ghazal, Peter, Cope, Andrew P.
Publicado en Nat Commun (2019)

An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway

por Robertson, Kevin A., Hsieh, Wei Yuan, Forster, Thorsten, Blanc, Mathieu, Lu, Hongjin, Crick, Peter J., Yutuc, Eylan, Watterson, Steven, Martin, Kimberly, Griffiths, Samantha J., Enright, Anton J., Yamamoto, Mami, Pradeepa, Madapura M., Lennox, Kimberly A., Behlke, Mark A., Talbot, Simon, Haas, Jürgen, Dölken, Lars, Griffiths, William J., Wang, Yuqin, Angulo, Ana, Ghazal, Peter
Publicado en PLoS Biol (2016)

The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response

por Blanc, Mathieu, Hsieh, Wei Yuan, Robertson, Kevin A., Kropp, Kai A., Forster, Thorsten, Shui, Guanghou, Lacaze, Paul, Watterson, Steven, Griffiths, Samantha J., Spann, Nathanael J., Meljon, Anna, Talbot, Simon, Krishnan, Kathiresan, Covey, Douglas F., Wenk, Markus R., Craigon, Marie, Ruzsics, Zsolts, Haas, Jürgen, Angulo, Ana, Griffiths, William J., Glass, Christopher K., Wang, Yuqin, Ghazal, Peter
Publicado 2013