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Host Defense against Viral Infection Involves Interferon Mediated Down-Regulation of Sterol Biosynthesis

Little is known about the protective role of inflammatory processes in modulating lipid metabolism in infection. Here we report an intimate link between the innate immune response to infection and regulation of the sterol metabolic network characterized by down-regulation of sterol biosynthesis by a...

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Autori principali: Blanc, Mathieu, Hsieh, Wei Yuan, Robertson, Kevin A., Watterson, Steven, Shui, Guanghou, Lacaze, Paul, Khondoker, Mizanur, Dickinson, Paul, Sing, Garwin, Rodríguez-Martín, Sara, Phelan, Peter, Forster, Thorsten, Strobl, Birgit, Müller, Matthias, Riemersma, Rudolph, Osborne, Timothy, Wenk, Markus R., Angulo, Ana, Ghazal, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050939/
https://ncbi.nlm.nih.gov/pubmed/21408089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000598
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