The ‘Ins and Outs’ of complement-driven immune responses

por Freeley, Simon, Kemper, Claudia, Le Friec, Gaëlle
Publicado en Immunol Rev (2016)

DAP10 associates with Ly49 receptors but contributes minimally to their expression and function in vivo

por Tassi, Ilaria, Le Friec, Gaelle, Gilfillan, Susan, Takai, Toshiyuki, Yokoyama, Wayne M., Colonna, Marco
Publicado 2009

Mouse PRDM9 DNA-Binding Specificity Determines Sites of Histone H3 Lysine 4 Trimethylation for Initiation of Meiotic Recombination

por Grey, Corinne, Barthès, Pauline, Chauveau-Le Friec, Gaëlle, Langa, Francina, Baudat, Frédéric, de Massy, Bernard
Publicado 2011

Dysregulated CD46 shedding interferes with Th1‐contraction in systemic lupus erythematosus

por Ellinghaus, Ursula, Cortini, Andrea, Pinder, Christopher L., Le Friec, Gaelle, Kemper, Claudia, Vyse, Timothy J.
Publicado en Eur J Immunol (2017)

Complement regulator CD46 temporally regulates cytokine production by conventional and unconventional T cells

por Cardone, John, Le Friec, Gaelle, Vantourout, Pierre, Roberts, Andrew, Fuchs, Anja, Jackson, Ian, Suddason, Tesha, Lord, Graham, Atkinson, John P, Cope, Andrew, Hayday, Adrian, Kemper, Claudia
Publicado 2010

The inhibitory receptor NKG2A sustains virus-specific CD8(+) T cells in response to a lethal poxvirus infection

por Rapaport, Aaron S., Schriewer, Jill, Gilfillan, Susan, Hembrador, Ed, Crump, Ryan, Plougastel, Beatrice F., Wang, Yaming, Le Friec, Gaelle, Gao, Jian, Cella, Marina, Pircher, Hanspeter, Yokoyama, Wayne M., Buller, R. Mark L., Colonna, Marco
Publicado en Immunity (2015)

Complement Regulates Nutrient Influx and Metabolic Reprogramming during Th1 Cell Responses

por Kolev, Martin, Dimeloe, Sarah, Le Friec, Gaelle, Navarini, Alexander, Arbore, Giuseppina, Povoleri, Giovanni A., Fischer, Marco, Belle, Réka, Loeliger, Jordan, Develioglu, Leyla, Bantug, Glenn R., Watson, Julie, Couzi, Lionel, Afzali, Behdad, Lavender, Paul, Hess, Christoph, Kemper, Claudia
Publicado en Immunity (2015)

Intracellular Complement Activation Sustains T Cell Homeostasis and Mediates Effector Differentiation

por Liszewski, M. Kathryn, Kolev, Martin, Le Friec, Gaelle, Leung, Marilyn, Bertram, Paula G., Fara, Antonella F., Subias, Marta, Pickering, Matthew C., Drouet, Christian, Meri, Seppo, Arstila, T. Petteri, Pekkarinen, Pirkka T., Ma, Margaret, Cope, Andrew, Reinheckel, Thomas, Rodriguez de Cordoba, Santiago, Afzali, Behdad, Atkinson, John P., Kemper, Claudia
Publicado 2013

Complement receptor CD46 co-stimulates optimal human CD8(+) T cell effector function via fatty acid metabolism

por Arbore, Giuseppina, West, Erin E., Rahman, Jubayer, Le Friec, Gaelle, Niyonzima, Nathalie, Pirooznia, Mehdi, Tunc, Ilker, Pavlidis, Polychronis, Powell, Nicholas, Li, Yuesheng, Liu, Poching, Servais, Aude, Couzi, Lionel, Fremeaux-Bacchi, Veronique, Placais, Leo, Ferraro, Alastair, Walsh, Patrick R., Kavanagh, David, Afzali, Behdad, Lavender, Paul, Lachmann, Helen J., Kemper, Claudia
Publicado en Nat Commun (2018)

The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells

por Perucha, Esperanza, Melchiotti, Rossella, Bibby, Jack A, Wu, Wing, Frederiksen, Klaus Stensgaard, Roberts, Ceri A., Hall, Zoe, LeFriec, Gaelle, Robertson, Kevin A., Lavender, Paul, Gerwien, Jens Gammeltoft, Taams, Leonie S., Griffin, Julian L., de Rinaldis, Emanuele, van Baarsen, Lisa G. M., Kemper, Claudia, Ghazal, Peter, Cope, Andrew P.
Publicado en Nat Commun (2019)

The CD46 and Jagged1 interaction is critical for human T helper 1 immunity

por Le Friec, Gaëlle, Sheppard, Devon, Whiteman, Pat, Karsten, Christian M., Shamoun, Salley Al-Tilib, Laing, Adam, Bugeon, Laurence, Dallman, Margaret J., Melchionna, Teresa, Chillakuri, Chandramouli, Smith, Richard A., Drouet, Christian, Couzi, Lionel, Fremeaux-Bacchi, Veronique, Köhl, Jörg, Waddington, Simon N., McDonnell, James M., Baker, Alastair, Handford, Penny A., Lea, Susan M., Kemper, Claudia
Publicado 2012