Non-Linear and Flexible Regions of the Human Notch1 Extracellular Domain Revealed by High-Resolution Structural Studies

Por Weisshuhn, Philip C., Sheppard, Devon, Taylor, Paul, Whiteman, Pat, Lea, Susan M., Handford, Penny A., Redfield, Christina
Publicado no Structure (2016)

Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands

Por Suckling, Richard J, Korona, Boguslawa, Whiteman, Pat, Chillakuri, Chandramouli, Holt, Laurie, Handford, Penny A, Lea, Susan M
Publicado no EMBO J (2017)

A Conserved Face of the Jagged/Serrate DSL Domain is Involved in Notch Trans-Activation and Cis-Inhibition

Por Cordle, Jemima, Johnson, Steven, Tay, Joyce Zi Yan, Roversi, Pietro, Wilkin, Marian, Hernandez-Diaz, Beatriz, Shimizu, Hideyuki, Jensen, Sacha, Whiteman, Pat, Jin, Boquan, Redfield, Christina, Baron, Martin, Lea, Susan M., Handford, Penny A.
Publicado em 2008

Molecular Basis for Jagged-1/Serrate Ligand Recognition by the Notch Receptor

Por Whiteman, Pat, de Madrid, Beatriz Hernandez, Taylor, Paul, Li, Demin, Heslop, Rebecca, Viticheep, Nattnee, Tan, Joyce Zi, Shimizu, Hideyuki, Callaghan, Juliana, Masiero, Massimo, Li, Ji Liang, Banham, Alison H., Harris, Adrian L., Lea, Susan M., Redfield, Christina, Baron, Martin, Handford, Penny A.
Publicado em 2013

Development of therapeutic anti-JAGGED1 antibodies for cancer therapy

Por Masiero, Massimo, Li, Demin, Whiteman, Pat, Bentley, Carol, Greig, Jenny, Hassanali, Tasneem, Watts, Sarah, Stribbling, Stephen, Yates, Jenna, Bealing, Ellen, Li, Ji-Liang, Chillakuri, Chandramouli, Sheppard, Devon, Serres, Sébastien, Sarmiento-Soto, Manuel, Larkin, James, Sibson, Nicola R., Handford, Penny A., Harris, Adrian L., Banham, Alison H.
Publicado no Mol Cancer Ther (2019)

The CD46 and Jagged1 interaction is critical for human T helper 1 immunity

Por Le Friec, Gaëlle, Sheppard, Devon, Whiteman, Pat, Karsten, Christian M., Shamoun, Salley Al-Tilib, Laing, Adam, Bugeon, Laurence, Dallman, Margaret J., Melchionna, Teresa, Chillakuri, Chandramouli, Smith, Richard A., Drouet, Christian, Couzi, Lionel, Fremeaux-Bacchi, Veronique, Köhl, Jörg, Waddington, Simon N., McDonnell, James M., Baker, Alastair, Handford, Penny A., Lea, Susan M., Kemper, Claudia
Publicado em 2012