Potent selective nonpeptidic inhibitors of human lung tryptase

Por Burgess, Laurence E., Newhouse, Bradley J., Ibrahim, Prabha, Rizzi, James, Kashem, Mohammed A., Hartman, Ann, Brandhuber, Barbara J., Wright, Clifford D., Thomson, David S., Vigers, Guy P. A., Koch, Kevin
Publicado em 1999

On-Target Efficacy of a HIF2α Antagonist in Preclinical Kidney Cancer Models

Por Cho, Hyejin, Du, Xinlin, Rizzi, James P., Liberzon, Ella, Chakraborty, Abhishek A., Gao, Wenhua, Carvo, Ingrid, Signoretti, Sabina, Bruick, Richard, Josey, John A., Wallace, Eli M., Kaelin, William G.
Publicado no Nature (2016)

UK-78,282, a novel piperidine compound that potently blocks the Kv1.3 voltage-gated potassium channel and inhibits human T cell activation

Por Hanson, Douglas C, Nguyen, Angela, Mather, Robert J, Rauer, Heiko, Koch, Kevin, Burgess, Laurence E, Rizzi, James P, Donovan, Carol B, Bruns, Matthew J, Canniff, Paul C, Cunningham, Ann C, Verdries, Kimberly A, Mena, Edward, Kath, John C, Gutman, George A, Cahalan, Michael D, Grissmer, Stephan, Chandy, K George
Publicado em 1999

Discovery of a Novel Class of Imidazo[1,2-a]Pyridines with Potent PDGFR Activity and Oral Bioavailability

Por Hicken, Erik J., Marmsater, Fred P., Munson, Mark C., Schlachter, Stephen T., Robinson, John E., Allen, Shelley, Burgess, Laurence E., DeLisle, Robert Kirk, Rizzi, James P., Topalov, George T., Zhao, Qian, Hicks, Julie M., Kallan, Nicholas C., Tarlton, Eugene, Allen, Andrew, Callejo, Michele, Cox, April, Rana, Sumeet, Klopfenstein, Nathalie, Woessner, Richard, Lyssikatos, Joseph P.
Publicado em 2013

Pexmetinib: a novel dual inhibitor of Tie-2 and p38 MAPK with efficacy in preclinical models of myelodysplastic syndromes and acute myeloid leukemia

Por Bachegowda, Lohith, Morrone, Kerry, Winski, Shannon L., Mantzaris, Ioannis, Bartenstein, Matthias, Ramachandra, Nandini, Giricz, Orsi, Sukrithan, Vineeth, Nwankwo, George, Shahnaz, Samira, Bhagat, Tushar, Bhattacharyya, Sanchari, Assal, Amer, Shastri, Aditi, Gordon-Mitchell, Shanisha, Pellagatti, Andrea, Boultwood, Jacqueline, Schinke, Carolina, Yu, Yiting, Guha, Chandan, Rizzi, James, Garrus, Jennifer, Brown, Suzy, Wollenberg, Lance, Hogeland, Grant, Wright, Dale, Munson, Mark, Rodriguez, Mareli, Gross, Stefan, Chantry, David, Zou, Yiyu, Platanias, Leonidas, Burgess, Laurence E., Pradhan, Kith, Steidl, Ulrich, Verma, Amit
Publicado no Cancer Res (2016)

Targeting Renal Cell Carcinoma with a HIF-2 antagonist

Por Chen, Wenfang, Hill, Haley, Christie, Alana, Kim, Min Soo, Holloman, Eboni, Pavia-Jimenez, Andrea, Homayoun, Farrah, Ma, Yuanqing, Patel, Nirav, Yell, Paul, Hao, Guiyang, Yousuf, Qurratulain, Joyce, Allison, Pedrosa, Ivan, Geiger, Heather, Zhang, He, Chang, Jenny, Gardner, Kevin H., Bruick, Richard K., Reeves, Catherine, Hwang, Tae Hyun, Courtney, Kevin, Frenkel, Eugene, Sun, Xiankai, Zojwalla, Naseem, Wong, Tai, Rizzi, James P., Wallace, Eli M., Josey, John A., Xie, Yang, Xie, Xian-Jin, Kapur, Payal, McKay, Renée M., Brugarolas, James
Publicado no Nature (2016)