Updates on novel therapies for metastatic renal cell carcinoma

Por Courtney, Kevin D., Choueiri, Toni K.
Publicado em 2010

MON-362 Undiagnosed Non-classic Congenital Adrenal Hyperplasia as a Driving Force for Persistent Hyperandrogenemia in Prostate Cancer

Por Awosanya, Tiwa, Hamidi, Oksana, Courtney, Kevin
Publicado no J Endocr Soc (2019)

The PI3K Pathway As Drug Target in Human Cancer

Por Courtney, Kevin D., Corcoran, Ryan B., Engelman, Jeffrey A.
Publicado em 2010

PI3K Enters Beta-Testing

Por Shaywitz, Adam J., Courtney, Kevin D., Patnaik, Akash, Cantley, Lewis C.
Publicado em 2008

Akt Inhibition Promotes ABCA1-Mediated Cholesterol Efflux to ApoA-I through Suppressing mTORC1

Por Dong, Fumin, Mo, Zhongcheng, Eid, Walaa, Courtney, Kevin C., Zha, Xiaohui
Publicado no PLoS One (2014)

Resolving kinetic intermediates during the regulated assembly and disassembly of fusion pores

Por Das, Debasis, Bao, Huan, Courtney, Kevin C., Wu, Lanxi, Chapman, Edwin R.
Publicado no Nat Commun (2020)

Congenital Adrenal Hyperplasia Causing Poor Response to Androgen Deprivation Therapy in Prostate Cancer

Por Kinaan, Mustafa, Hamidi, Oksana, Yau, Hanford, Courtney, Kevin D, Eraslan, Akin, Simon, Kenneth
Publicado no J Endocr Soc (2020)

Comment on ‘Orthogonal lipid sensors identify transbilayer asymmetry of plasma membrane cholesterol’

Por Courtney, Kevin C, Fung, Karen YY, Maxfield, Frederick R, Fairn, Gregory D, Zha, Xiaohui
Publicado no eLife (2018)

mTORC1 activates SREBP-2 by suppressing cholesterol trafficking to lysosomes in mammalian cells

Por Eid, Walaa, Dauner, Kristin, Courtney, Kevin C., Gagnon, AnneMarie, Parks, Robin J., Sorisky, Alexander, Zha, Xiaohui
Publicado no Proc Natl Acad Sci U S A (2017)

Oncogenic Abl and Src tyrosine kinases elicit the ubiquitin-dependent degradation of target proteins through a Ras-independent pathway

Por Dai, Zonghan, Quackenbush, Robert C., Courtney, Kevin D., Grove, Matthew, Cortez, David, Reuther, Gary W., Pendergast, Ann Marie
Publicado em 1998

Beyond Amphiphilic Balance: Changing Subunit Stereochemistry Alters the Pore-Forming Activity of Nylon-3 Polymers

Por Liu, Lei, Courtney, Kevin C., Huth, Sean W., Rank, Leslie A., Weisblum, Bernard, Chapman, Edwin R., Gellman, Samuel H.
Publicado no J Am Chem Soc (2021)

Identification of CDCP1 as a hypoxia-inducible factor 2α (HIF-2α) target gene that is associated with survival in clear cell renal cell carcinoma patients

Por Emerling, Brooke M., Benes, Cyril H., Poulogiannis, George, Bell, Eric L., Courtney, Kevin, Liu, Hui, Choo-Wing, Rayman, Bellinger, Gary, Tsukazawa, Kazumi S., Brown, Victoria, Signoretti, Sabina, Soltoff, Stephen P., Cantley, Lewis C.
Publicado em 2013

Aberrant corticosteroid metabolism in tumor cells enables GR takeover in enzalutamide resistant prostate cancer

Por Li, Jianneng, Alyamani, Mohammad, Zhang, Ao, Chang, Kai-Hsiung, Berk, Michael, Li, Zhenfei, Zhu, Ziqi, Petro, Marianne, Magi-Galluzzi, Cristina, Taplin, Mary-Ellen, Garcia, Jorge A, Courtney, Kevin, Klein, Eric A, Sharifi, Nima
Publicado no eLife (2017)

Phase I Dose-Escalation Trial of PT2385, a First-in-Class Hypoxia-Inducible Factor-2α Antagonist in Patients With Previously Treated Advanced Clear Cell Renal Cell Carcinoma

Por Courtney, Kevin D., Infante, Jeffrey R., Lam, Elaine T., Figlin, Robert A., Rini, Brian I., Brugarolas, James, Zojwalla, Naseem J., Lowe, Ann M., Wang, Keshi, Wallace, Eli M., Josey, John A., Choueiri, Toni K.
Publicado no J Clin Oncol (2018)

Blocking Monocytic Myeloid-Derived Suppressor Cell Function via Anti-DC-HIL/GPNMB Antibody Restores the In Vitro Integrity of T Cells from Cancer Patients

Por Kobayashi, Masato, Chung, Jin-Sung, Beg, Muhammad, Arriaga, Yull, Verma, Udit, Courtney, Kevin, Mansour, John, Haley, Barbara, Khan, Saad, Horiuchi, Yutaka, Ramani, Vijay, Harker, David, Gopal, Purva, Araghizadeh, Farshid, Cruz, Ponciano D., Ariizumi, Kiyoshi
Publicado no Clin Cancer Res (2018)

Stereotactic Ablative Radiation Therapy (SAbR) Used to Defer Systemic Therapy in Oligometastatic Renal Cell Cancer

Por Zhang, Yuanyuan, Schoenhals, Jonathan, Christie, Alana, Mohamad, Osama, Wang, Chiachien, Bowman, Isaac, Singla, Nirmish, Hammers, Hans, Courtney, Kevin, Bagrodia, Aditya, Margulis, Vitaly, Desai, Neil, Garant, Aurelie, Choy, Hak, Brugarolas, James, Timmerman, Robert, Hannan, Raquibul
Publicado no Int J Radiat Oncol Biol Phys (2019)

Improved Survival Outcomes for Kidney Cancer Patients with Brain Metastases

Por Bowman, I.Alex, Bent, Alisha, Le, Tri, Christie, Alana, Wardak, Zabi, Arriaga, Yull, Courtney, Kevin, Hammers, Hans, Barnett, Samuel, Mickey, Bruce, Patel, Toral, Whitworth, Tony, Stojadinovic, Strahinja, Hannan, Raquibul, Nedzi, Lucien, Timmerman, Robert, Brugarolas, James
Publicado no Clin Genitourin Cancer (2018)

A Phase I Study of Everolimus and Docetaxel in Patients With Castration-Resistant Prostate Cancer

Por Courtney, Kevin D., Manola, Judith B., Elfiky, Aymen A., Ross, Robert, Oh, William K., Yap, Jeffrey T., Van den Abbeele, Annick D., Ryan, Christopher W., Beer, Tomasz M., Loda, Massimo, Priolo, Carmen, Kantoff, Philip, Taplin, Mary-Ellen
Publicado no Clin Genitourin Cancer (2014)

Isotope tracing of human clear cell renal cell carcinomas demonstrates suppressed glucose oxidation in vivo

Por Courtney, Kevin D., Bezwada, Divya, Mashimo, Tomoyuki, Pichumani, Kumar, Vemireddy, Vamsidhara, Funk, Alexander M., Wimberly, Jennifer, McNeil, Sarah S., Kapur, Payal, Lotan, Yair, Margulis, Vitaly, Cadeddu, Jeffrey A., Pedrosa, Ivan, DeBerardinis, Ralph J., Malloy, Craig R., Bachoo, Robert M., Maher, Elizabeth A.
Publicado no Cell Metab (2018)

Safety and efficacy of concurrent immune checkpoint inhibitors and hypofractionated body radiotherapy

Por Mohamad, Osama, Diaz de Leon, Alberto, Schroeder, Samuel, Leiker, Andrew, Christie, Alana, Zhang-Velten, Elizabeth, Trivedi, Lakshya, Khan, Saad, Desai, Neil B, Laine, Aaron, Albuquerque, Kevin, Iyengar, Puneeth, Arriaga, Yull, Courtney, Kevin, Gerber, David E., Hammers, Hans, Choy, Hak, Timmerman, Robert, Brugarolas, James, Hannan, Raquibul
Publicado no Oncoimmunology (2018)