AR Signaling in Prostate Cancer Regulates a Feed-Forward Mechanism of Androgen Synthesis by Way of HSD3B1 Upregulation

著者: Hettel, Daniel, Zhang, Ao, Alyamani, Mohammad, Berk, Michael, Sharifi, Nima
出版年 Endocrinology (2018)

Development and validation of a novel LC–MS/MS method for simultaneous determination of abiraterone and its seven steroidal metabolites in human serum: Innovation in separation of...

著者: Alyamani, Mohammad, Li, Zhenfei, Upadhyay, Sunil K., Anderson, David J., Auchus, Richard J., Sharifi, Nima
出版年 J Steroid Biochem Mol Biol (2016)

Rapid and structure-specific cellular uptake of selected steroids

著者: McManus, Jeffrey M., Bohn, Kelsey, Alyamani, Mohammad, Chung, Yoon-Mi, Klein, Eric A., Sharifi, Nima
出版年 PLoS One (2019)

Steroidogenic metabolism of galeterone reveals a diversity of biochemical activities

著者: Alyamani, Mohammad, Li, Zhenfei, Berk, Michael, Li, Jianneng, Tang, Jingjie, Upadhyay, Sunil, Auchus, Richard J., Sharifi, Nima
出版年 Cell Chem Biol (2017)

Conversion of abiraterone to D4A drives antitumor activity in prostate cancer

著者: Li, Zhenfei, Bishop, Andrew, Alyamani, Mohammad, Garcia, Jorge A., Dreicer, Robert, Bunch, Dustin, Liu, Jiayan, Upadhyay, Sunil K., Auchus, Richard J., Sharifi, Nima
出版年 Nature (2015)

Hexose-6-phosphate dehydrogenase blockade reverses prostate cancer drug resistance in xenograft models by glucocorticoid inactivation

著者: Jianneng Li, Berk, Michael, Alyamani, Mohammad, Sabharwal, Navin, Goins, Christopher, Alvarado, Joseph, Baratchian, Mehdi, Zhu, Ziqi, Stauffer, Shaun, Klein, Eric A., Sharifi, Nima
出版年 Sci Transl Med (2021)

Redirecting abiraterone metabolism to fine tune prostate cancer anti-androgen therapy

著者: Li, Zhenfei, Alyamani, Mohammad, Li, Jianneng, Rogacki, Kevin, Abazeed, Mohamed, Upadhyay, Sunil K., Balk, Steven P., Taplin, Mary-Ellen, Auchus, Richard J., Sharifi, Nima
出版年 Nature (2016)

SUN-739 Next Generation AR Antagonists Increase Systemic Active Glucocorticoid Exposure by Altering Glucocorticoid Metabolism

著者: Alyamani, Mohammad, Sharifi, Nima, Li, Jianbo, Patel, Mona, Berk, Michael, Taylor, Susan, Przybycin, Christopher, Posadas, Edwin M, Madan, Ravi, Gulley, James L, Rini, Brian I, Garcia, Jorgi A, Klein, Eric A
出版年 J Endocr Soc (2020)

Aberrant corticosteroid metabolism in tumor cells enables GR takeover in enzalutamide resistant prostate cancer

著者: Li, Jianneng, Alyamani, Mohammad, Zhang, Ao, Chang, Kai-Hsiung, Berk, Michael, Li, Zhenfei, Zhu, Ziqi, Petro, Marianne, Magi-Galluzzi, Cristina, Taplin, Mary-Ellen, Garcia, Jorge A, Courtney, Kevin, Klein, Eric A, Sharifi, Nima
出版年 eLife (2017)

HSD3B1(1245A>C) variant regulates dueling abiraterone metabolite effects in prostate cancer

著者: Alyamani, Mohammad, Emamekhoo, Hamid, Park, Sunho, Taylor, Jennifer, Almassi, Nima, Upadhyay, Sunil, Tyler, Allison, Berk, Michael P., Hu, Bo, Hwang, Tae Hyun, Figg, William Douglas, Peer, Cody J., Chien, Caly, Koshkin, Vadim S., Mendiratta, Prateek, Grivas, Petros, Rini, Brian, Garcia, Jorge, Auchus, Richard J., Sharifi, Nima
出版年 J Clin Invest (2018)

Association of Tissue Abiraterone Levels and SLCO Genotype with Intraprostatic Steroids and Pathologic Response in Men with High-Risk Localized Prostate Cancer

著者: Mostaghel, Elahe A, Cho, Eunpi, Zhang, Ailin, Alyamani, Mohammad, Kaipainen, Arja, Green, Sean, Marck, Brett T, Sharifi, Nima, Wright, Jonathan L, Gulati, Roman, True, Lawrence D, Loda, Massimo, Matsumoto, Alvin M, Tamae, Daniel, Penning, Trevor M, Balk, Steven P, Kantoff, Phillip W, Nelson, Peter S, Taplin, Mary-Ellen, Montgomery, R Bruce
出版年 Clin Cancer Res (2017)

HSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma

著者: Zein, Joe, Gaston, Benjamin, Bazeley, Peter, DeBoer, Mark D., Igo, Robert P., Bleecker, Eugene R., Meyers, Deborah, Comhair, Suzy, Marozkina, Nadzeya V., Cotton, Calvin, Patel, Mona, Alyamani, Mohammad, Xu, Weiling, Busse, William W., Calhoun, William J., Ortega, Victor, Hawkins, Gregory A., Castro, Mario, Chung, Kian Fan, Fahy, John V., Fitzpatrick, Anne M., Israel, Elliot, Jarjour, Nizar N., Levy, Bruce, Mauger, David T., Moore, Wendy C., Noel, Patricia, Peters, Stephen P., Teague, W. Gerald, Wenzel, Sally E., Erzurum, Serpil C., Sharifi, Nima
出版年 Proc Natl Acad Sci U S A (2020)