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Oncogenic Abl and Src tyrosine kinases elicit the ubiquitin-dependent degradation of target proteins through a Ras-independent pathway

Oncogenic forms of the Abl and Src tyrosine kinases trigger the destruction of the Abi proteins, a family of Abl-interacting proteins that antagonize the oncogenic potential of Abl after overexpression in fibroblasts. The destruction of the Abi proteins requires tyrosine kinase activity and is depen...

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Detalhes bibliográficos
Main Authors: Dai, Zonghan, Quackenbush, Robert C., Courtney, Kevin D., Grove, Matthew, Cortez, David, Reuther, Gary W., Pendergast, Ann Marie
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC316832/
https://ncbi.nlm.nih.gov/pubmed/9585502
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