A Phase I Study of Everolimus and Docetaxel in Patients With Castration-Resistant Prostate Cancer

Activation of the phosphoinositide 3-kinase signaling cascade, often through loss of the phosphatase and tensin homologue deleted on chromosome 10 (PTEN) tumor suppressor, is frequent in castration-resistant prostate cancer (CRPC). We assessed the safety and efficacy of combining the mammalian targe...

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Detalhes bibliográficos
Publicado no:Clin Genitourin Cancer
Main Authors: Courtney, Kevin D., Manola, Judith B., Elfiky, Aymen A., Ross, Robert, Oh, William K., Yap, Jeffrey T., Van den Abbeele, Annick D., Ryan, Christopher W., Beer, Tomasz M., Loda, Massimo, Priolo, Carmen, Kantoff, Philip, Taplin, Mary-Ellen
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418946/
https://ncbi.nlm.nih.gov/pubmed/25450031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clgc.2014.08.007
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