A Phase I Study of Everolimus and Docetaxel in Patients With Castration-Resistant Prostate Cancer

Activation of the phosphoinositide 3-kinase signaling cascade, often through loss of the phosphatase and tensin homologue deleted on chromosome 10 (PTEN) tumor suppressor, is frequent in castration-resistant prostate cancer (CRPC). We assessed the safety and efficacy of combining the mammalian targe...

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I publikationen:Clin Genitourin Cancer
Huvudupphovsmän: Courtney, Kevin D., Manola, Judith B., Elfiky, Aymen A., Ross, Robert, Oh, William K., Yap, Jeffrey T., Van den Abbeele, Annick D., Ryan, Christopher W., Beer, Tomasz M., Loda, Massimo, Priolo, Carmen, Kantoff, Philip, Taplin, Mary-Ellen
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418946/
https://ncbi.nlm.nih.gov/pubmed/25450031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clgc.2014.08.007
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