A Phase I Study of Everolimus and Docetaxel in Patients With Castration-Resistant Prostate Cancer

Activation of the phosphoinositide 3-kinase signaling cascade, often through loss of the phosphatase and tensin homologue deleted on chromosome 10 (PTEN) tumor suppressor, is frequent in castration-resistant prostate cancer (CRPC). We assessed the safety and efficacy of combining the mammalian targe...

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Veröffentlicht in:Clin Genitourin Cancer
Hauptverfasser: Courtney, Kevin D., Manola, Judith B., Elfiky, Aymen A., Ross, Robert, Oh, William K., Yap, Jeffrey T., Van den Abbeele, Annick D., Ryan, Christopher W., Beer, Tomasz M., Loda, Massimo, Priolo, Carmen, Kantoff, Philip, Taplin, Mary-Ellen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418946/
https://ncbi.nlm.nih.gov/pubmed/25450031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clgc.2014.08.007
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