Dimethyl fumarate and the oleanane triterpenoids, CDDO-imidazolide and CDDO-methyl ester, both activate the Nrf2 pathway but have opposite effects in the A/J model of lung carcinog...

Yazar: To, Ciric, Ringelberg, Carol S., Royce, Darlene B., Williams, Charlotte R., Risingsong, Renee, Sporn, Michael B., Liby, Karen T.
Yayımlandı Carcinogenesis (2015)

Triterpenoids CDDO-methylester or CDDO-ethylamide and rexinoids LG100268 or NRX194204 for prevention and treatment of lung cancer in mice

Yazar: Liby, Karen, Risingsong, Renee, Royce, Darlene B., Williams, Charlotte R., Ma, Tian, Yore, Mark M., Sporn, Michael B.
Baskı/Yayın Bilgisi 2009

Synthetic triterpenoids prolong survival in a transgenic mouse model of pancreatic cancer

Yazar: Liby, Karen, Royce, Darlene B., Risingsong, Renee, Williams, Charlotte R., Maitra, Anirban, Hruban, Ralph H., Sporn, Michael B.
Baskı/Yayın Bilgisi 2010

CDDO-Methyl ester delays breast cancer development in BRCA1-mutated mice

Yazar: Kim, Eun-Hee, Deng, Chuxia, Sporn, Michael B., Royce, Darlene B., Risingsong, Renee, Williams, Charlotte R., Liby, Karen T.
Baskı/Yayın Bilgisi 2011

The PARP inhibitors, veliparib and olaparib, are effective chemopreventive agents for delaying mammary tumor development in BRCA1-deficient mice

Yazar: To, Ciric, Kim, Eun-Hee, Royce, Darlene B., Williams, Charlotte R., Collins, Ryan M., Risingsong, Renee, Sporn, Michael B., Liby, Karen T.
Baskı/Yayın Bilgisi 2014

Neuroprotective effect of Nrf2/ARE Activators, CDDO-ethylamide and CDDO-trifluoroethylamide in a Mouse Model of Amyotrophic Lateral Sclerosis

Yazar: Neymotin, Arie, Calingasan, Noel Y., Wille, Elizabeth, Naseri, Nima, Petri, Susanne, Damiano, Maria, Liby, Karen T., Risingsong, Renee, Sporn, Michael, Beal, M. Flint, Kiaei, Mahmoud
Baskı/Yayın Bilgisi 2011

The combination of the histone deacetylase inhibitor vorinostat and synthetic triterpenoids reduces tumorigenesis in mouse models of cancer

Yazar: Tran, Kim, Risingsong, Renee, B.Royce, Darlene, Williams, Charlotte R., Sporn, Michael B., Pioli, Patricia A., Gediya, Lalji K., Njar, Vincent C., Liby, Karen T.
Baskı/Yayın Bilgisi 2013

Design, synthesis, and anti-inflammatory activity both in vitro and in vivo of new betulinic acid analogues having an enone functionality in ring A

Yazar: Honda, Tadashi, Liby, Karen T., Su, Xiaobo, Sundararajan, Chitra, Honda, Yukiko, Suh, Nanjoo, Risingsong, Renee, Williams, Charlotte R., Royce, Darlene B., Sporn, Michael B., Gribble, Gordon W.
Baskı/Yayın Bilgisi 2006

Extremely potent triterpenoid inducers of the phase 2 response: Correlations of protection against oxidant and inflammatory stress

Yazar: Dinkova-Kostova, Albena T., Liby, Karen T., Stephenson, Katherine K., Holtzclaw, W. David, Gao, Xiangqun, Suh, Nanjoo, Williams, Charlotte, Risingsong, Renee, Honda, Tadashi, Gribble, Gordon W., Sporn, Michael B., Talalay, Paul
Baskı/Yayın Bilgisi 2005

Prevention and Treatment of Experimental Estrogen Receptor – Negative Mammary Carcinogenesis by the Synthetic Triterpenoid CDDO-Methyl Ester and the Rexinoid LG100268

Yazar: Liby, Karen, Risingsong, Renee, Royce, Darlene B., Williams, Charlotte R., Yore, Mark M., Honda, Tadashi, Gribble, Gordon W., Lamph, William W., Vannini, Nicola, Sogno, Ilaria, Albini, Adriana, Sporn, Michael B.
Yayımlandı Clin Cancer Res (2008)

Neuroprotective Effects of the Triterpenoid, CDDO Methyl Amide, a Potent Inducer of Nrf2-Mediated Transcription

Yazar: Yang, Lichuan, Calingasan, Noel Y., Thomas, Bobby, Chaturvedi, Rajnish K., Kiaei, Mahmoud, Wille, Elizabeth J., Liby, Karen T., Williams, Charlotte, Royce, Darlene, Risingsong, Renee, Musiek, Eric S., Morrow, Jason D., Sporn, Michael, Beal, M. Flint
Baskı/Yayın Bilgisi 2009

The rexinoid LG100268 and the synthetic triterpenoid CDDO-methyl amide are more potent than erlotinib for prevention of mouse lung carcinogenesis

Yazar: Liby, Karen, Black, Candice C., Royce, Darlene B., Williams, Charlotte R., Risingsong, Renee, Yore, Mark M., Liu, Xi, Honda, Tadashi, Gribble, Gordon W., Lamph, William W., Sporn, Thomas A., Dmitrovsky, Ethan, Sporn, Michael B.
Baskı/Yayın Bilgisi 2008

A novel acetylenic tricyclic bis-(cyano enone) potently induces phase 2 cytoprotective pathways and blocks liver carcinogenesis induced by aflatoxin

Yazar: Liby, Karen, Yore, Mark M., Roebuck, Bill D., Baumgartner, Karen J., Honda, Tadashi, Sundararajan, Chitra, Yoshizawa, Hidenori, Gribble, Gordon W., Williams, Charlotte R., Risingsong, Renee, Royce, Darlene B., Dinkova-Kostova, Albena T., Stephenson, Katherine K., Egner, Patricia A., Yates, Melinda S., Groopman, John D., Kensler, Thomas W., Sporn, Michael B.
Baskı/Yayın Bilgisi 2008