Triterpenoids CDDO-methylester or CDDO-ethylamide and rexinoids LG100268 or NRX194204 for prevention and treatment of lung cancer in mice

We tested members of two non-cytotoxic classes of drugs, synthetic oleanane triterpenoids and rexinoids, both as individual agents and in combination, for the prevention and treatment of carcinogenesis in a highly relevant animal model of lung cancer. Lung adenocarcinomas were induced in A/J mice by...

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Bibliographic Details
Main Authors: Liby, Karen, Risingsong, Renee, Royce, Darlene B., Williams, Charlotte R., Ma, Tian, Yore, Mark M., Sporn, Michael B.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818234/
https://ncbi.nlm.nih.gov/pubmed/19952361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-09-0085
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