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CDDO-Methyl ester delays breast cancer development in BRCA1-mutated mice

The breast cancer-associated gene 1 (BRCA1) is the most frequently mutated tumor suppressor gene in familial breast cancers. Mutations in BRCA1 also predispose to other types of cancers, pointing to a fundamental role of this pathway in tumor suppression and emphasizing the need for effective chemop...

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Библиографические подробности
Главные авторы: Kim, Eun-Hee, Deng, Chuxia, Sporn, Michael B., Royce, Darlene B., Risingsong, Renee, Williams, Charlotte R., Liby, Karen T.
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252488/
https://ncbi.nlm.nih.gov/pubmed/21933912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-11-0359
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