The PARP inhibitors, veliparib and olaparib, are effective chemopreventive agents for delaying mammary tumor development in BRCA1-deficient mice

Poly-ADP ribose polymerase (PARP) inhibitors are effective for the treatment of BRCA-deficient tumors. Women with these mutations have an increased risk of developing breast cancer and would benefit from effective chemoprevention. This study examines whether the PARP inhibitors, veliparib and olapar...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: To, Ciric, Kim, Eun-Hee, Royce, Darlene B., Williams, Charlotte R., Collins, Ryan M., Risingsong, Renee, Sporn, Michael B., Liby, Karen T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4089992/
https://ncbi.nlm.nih.gov/pubmed/24817481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-14-0047
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi