The PARP inhibitors, veliparib and olaparib, are effective chemopreventive agents for delaying mammary tumor development in BRCA1-deficient mice

Poly-ADP ribose polymerase (PARP) inhibitors are effective for the treatment of BRCA-deficient tumors. Women with these mutations have an increased risk of developing breast cancer and would benefit from effective chemoprevention. This study examines whether the PARP inhibitors, veliparib and olapar...

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Autores principales: To, Ciric, Kim, Eun-Hee, Royce, Darlene B., Williams, Charlotte R., Collins, Ryan M., Risingsong, Renee, Sporn, Michael B., Liby, Karen T.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4089992/
https://ncbi.nlm.nih.gov/pubmed/24817481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-14-0047
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