Actin up for Hippo

Por Richardson, Helena E
Publicado em 2011

Death takes a holiday—non-apoptotic role for caspases in cell migration and invasion

Por Portela, Marta, Richardson, Helena E
Publicado em 2013

scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila

Por Brumby, Anthony M., Richardson, Helena E.
Publicado em 2003

lgl Regulates the Hippo Pathway Independently of Fat/Dachs, Kibra/Expanded/Merlin and dRASSF/dSTRIPAK

Por Parsons, Linda M., Grzeschik, Nicola A., Richardson, Helena E.
Publicado em 2014

Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signaling

Por Doggett, Karen, Grusche, Felix A, Richardson, Helena E, Brumby, Anthony M
Publicado em 2011

Regulation of Notch signaling and endocytosis by the Lgl neoplastic tumor suppressor

Por Portela, Marta, Parsons, Linda M, Grzeschik, Nicola A, Richardson, Helena E
Publicado no Cell Cycle (2015)

Lgl/aPKC and Crb regulate the Salvador/Warts/Hippo pathway

Por Parsons, Linda M, Grzeschik, Nicola A, Allott, Melinda L, Richardson, Helena E
Publicado em 2010

In Drosophila, RhoGEF2 cooperates with activated Ras in tumorigenesis through a pathway involving Rho1–Rok–Myosin-II and JNK signalling

Por Khoo, Peytee, Allan, Kirsten, Willoughby, Lee, Brumby, Anthony M., Richardson, Helena E.
Publicado em 2013

Wingless signaling directly regulates cyclin E expression in proliferating embryonic PNS precursor cells

Por Deb, Dilip K., Tanaka-Matakatsu, Miho, Jones, Lynn, Richardson, Helena E., Du, Wei
Publicado em 2008

Abnormalities in cell proliferation and apico-basal cell polarity are separable in Drosophila lgl mutant clones in the developing eye

Por Grzeschik, Nicola A., Amin, Nancy, Secombe, Julie, Brumby, Anthony M., Richardson, Helena E.
Publicado em 2007

scribble mutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs

Por Leong, Gregory R, Goulding, Karen R, Amin, Nancy, Richardson, Helena E, Brumby, Anthony M
Publicado em 2009

Cooperation of the BTB-Zinc finger protein, Abrupt, with cytoskeletal regulators in Drosophila epithelial tumorigenesis

Por Turkel, Nezaket, Portela, Marta, Poon, Carole, Li, Jason, Brumby, Anthony M., Richardson, Helena E.
Publicado no Biol Open (2015)

BTB-Zinc Finger Oncogenes Are Required for Ras and Notch-Driven Tumorigenesis in Drosophila

Por Doggett, Karen, Turkel, Nezaket, Willoughby, Lee F., Ellul, Jason, Murray, Michael J., Richardson, Helena E., Brumby, Anthony M.
Publicado no PLoS One (2015)

The lethal giant larvae tumour suppressor mutation requires dMyc oncoprotein to promote clonal malignancy

Por Froldi, Francesca, Ziosi, Marcello, Garoia, Flavio, Pession, Andrea, Grzeschik, Nicola A, Bellosta, Paola, Strand, Dennis, Richardson, Helena E, Pession, Annalisa, Grifoni, Daniela
Publicado em 2010

An in vivo large-scale chemical screening platform using Drosophila for anti-cancer drug discovery

Por Willoughby, Lee F., Schlosser, Tanja, Manning, Samuel A., Parisot, John P., Street, Ian P., Richardson, Helena E., Humbert, Patrick O., Brumby, Anthony M.
Publicado em 2013

Identification of Novel Ras-Cooperating Oncogenes in Drosophila melanogaster: A RhoGEF/Rho-Family/JNK Pathway Is a Central Driver of Tumorigenesis

Por Brumby, Anthony M., Goulding, Karen R., Schlosser, Tanja, Loi, Sherene, Galea, Ryan, Khoo, Peytee, Bolden, Jessica E., Aigaki, Toshiro, Humbert, Patrick O., Richardson, Helena E.
Publicado em 2011

The BTB-zinc Finger Transcription Factor Abrupt Acts as an Epithelial Oncogene in Drosophila melanogaster through Maintaining a Progenitor-like Cell State

Por Turkel, Nezaket, Sahota, Virender K., Bolden, Jessica E., Goulding, Karen R., Doggett, Karen, Willoughby, Lee F., Blanco, Enrique, Martin-Blanco, Enrique, Corominas, Montserrat, Ellul, Jason, Aigaki, Toshiro, Richardson, Helena E., Brumby, Anthony M.
Publicado em 2013

The Brm-HDAC3-Erm repressor complex suppresses dedifferentiation in Drosophila type II neuroblast lineages

Por Koe, Chwee Tat, Li, Song, Rossi, Fabrizio, Wong, Jack Jing Lin, Wang, Yan, Zhang, Zhizhuo, Chen, Keng, Aw, Sherry Shiying, Richardson, Helena E, Robson, Paul, Sung, Wing-Kin, Yu, Fengwei, Gonzalez, Cayetano, Wang, Hongyan
Publicado em 2014