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scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila

Cancer is a multistep process involving cooperation between oncogenic or tumor suppressor mutations and interactions between the tumor and surrounding normal tissue. Here we present the first description of cooperative tumorigenesis in Drosophila, by using a system that mimics the development of tum...

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Autors principals: Brumby, Anthony M., Richardson, Helena E.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC275405/
https://ncbi.nlm.nih.gov/pubmed/14592975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg548
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