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lgl Regulates the Hippo Pathway Independently of Fat/Dachs, Kibra/Expanded/Merlin and dRASSF/dSTRIPAK

In both Drosophila and mammalian systems, the Hippo (Hpo) signalling pathway controls tissue growth by inhibiting cell proliferation and promoting apoptosis. The core pathway consists of a protein kinase Hpo (MST1/2 in mammals) that is regulated by a number of upstream inputs including Drosophila Ra...

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Detalhes bibliográficos
Main Authors: Parsons, Linda M., Grzeschik, Nicola A., Richardson, Helena E.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074808/
https://ncbi.nlm.nih.gov/pubmed/24743776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers6020879
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