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Kibra and Merlin activate the Hippo pathway spatially distinct from and independent of Expanded

The Hippo pathway is emerging as a key evolutionarily conserved signaling mechanism that controls organ size. Three membrane-associated proteins, Kibra, Merlin, and Expanded regulate pathway activity, but the precise molecular mechanism by which they function is still poorly understood. Here we prov...

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Bibliografische gegevens
Gepubliceerd in:Dev Cell
Hoofdauteurs: Su, Ting, Ludwig, Michael Z., Xu, Jiajie, Fehon, Richard G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414729/
https://ncbi.nlm.nih.gov/pubmed/28292426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.02.004
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