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Hippo Pathway Phylogenetics Predicts Monoubiquitylation of Salvador and Merlin/Nf2
Recently we employed phylogenetics to predict that the cellular interpretation of TGF-β signals is modulated by monoubiquitylation cycles affecting the Smad4 signal transducer/tumor suppressor. This prediction was subsequently validated by experiments in flies, frogs and mammalian cells. Here we app...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3522738/ https://ncbi.nlm.nih.gov/pubmed/23272121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051599 |
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