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Distinct Molecular Evolutionary Mechanisms Underlie the Functional Diversification of the Wnt and TGFβ Signaling Pathways

The canonical Wnt pathway is one of the oldest and most functionally diverse of animal intercellular signaling pathways. Though much is known about loss-of-function phenotypes for Wnt pathway components in several model organisms, the question of how this pathway achieved its current repertoire of f...

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Autori principali: Konikoff, Charlotte E., Wisotzkey, Robert G., Stinchfield, Michael J., Newfeld, Stuart J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer-Verlag 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874024/
https://ncbi.nlm.nih.gov/pubmed/20339843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00239-010-9337-z
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