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Negative feedback couples Hippo pathway activation with Kibra degradation independent of Yorkie-mediated transcription

The Hippo (Hpo) pathway regulates tissue growth in many animals. Multiple upstream components promote Hpo pathway activity, but the organization of these different inputs, the degree of crosstalk between them, and whether they are regulated in a distinct manner is not well understood. Kibra (Kib) ac...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Tokamov, Sherzod A, Su, Ting, Ullyot, Anne, Fehon, Richard G
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7895526/
https://ncbi.nlm.nih.gov/pubmed/33555257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.62326
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