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Usp7 regulates Hippo pathway through deubiquitinating the transcriptional coactivator Yorkie
The Hippo pathway plays an important role in organ development and adult tissue homeostasis, and its deregulation has been implicated in many cancers. The Hippo signaling relies on a core kinase cascade culminating in phosphorylation of the transcription coactivator Yorkie (Yki). Although Yki is the...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6345853/ https://ncbi.nlm.nih.gov/pubmed/30679505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08334-7 |
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