Usp7 regulates Hippo pathway through deubiquitinating the transcriptional coactivator Yorkie

The Hippo pathway plays an important role in organ development and adult tissue homeostasis, and its deregulation has been implicated in many cancers. The Hippo signaling relies on a core kinase cascade culminating in phosphorylation of the transcription coactivator Yorkie (Yki). Although Yki is the...

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Udgivet i:Nat Commun
Main Authors: Sun, Xiaohan, Ding, Yan, Zhan, Meixiao, Li, Yan, Gao, Dongqing, Wang, Guiping, Gao, Yang, Li, Yong, Wu, Shian, Lu, Ligong, Liu, Qingxin, Zhou, Zizhang
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345853/
https://ncbi.nlm.nih.gov/pubmed/30679505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08334-7
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