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Regulation of Notch signaling and endocytosis by the Lgl neoplastic tumor suppressor

The evolutionarily conserved neoplastic tumor suppressor protein, Lethal (2) giant larvae (Lgl), plays roles in cell polarity and tissue growth via regulation of the Hippo pathway. In our recent study, we showed that in the developing Drosophila eye epithelium, depletion of Lgl leads to increased li...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Cycle
Main Authors: Portela, Marta, Parsons, Linda M, Grzeschik, Nicola A, Richardson, Helena E
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613855/
https://ncbi.nlm.nih.gov/pubmed/25789785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1026515
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