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Regulation of Notch signaling and endocytosis by the Lgl neoplastic tumor suppressor

The evolutionarily conserved neoplastic tumor suppressor protein, Lethal (2) giant larvae (Lgl), plays roles in cell polarity and tissue growth via regulation of the Hippo pathway. In our recent study, we showed that in the developing Drosophila eye epithelium, depletion of Lgl leads to increased li...

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Foilsithe in:Cell Cycle
Main Authors: Portela, Marta, Parsons, Linda M, Grzeschik, Nicola A, Richardson, Helena E
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2015
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613855/
https://ncbi.nlm.nih.gov/pubmed/25789785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1026515
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