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Regulation of Notch signaling and endocytosis by the Lgl neoplastic tumor suppressor

The evolutionarily conserved neoplastic tumor suppressor protein, Lethal (2) giant larvae (Lgl), plays roles in cell polarity and tissue growth via regulation of the Hippo pathway. In our recent study, we showed that in the developing Drosophila eye epithelium, depletion of Lgl leads to increased li...

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Détails bibliographiques
Publié dans:Cell Cycle
Auteurs principaux: Portela, Marta, Parsons, Linda M, Grzeschik, Nicola A, Richardson, Helena E
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613855/
https://ncbi.nlm.nih.gov/pubmed/25789785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1026515
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