Translational Research Epigenomics

Por Replogle, Joseph M., De Jager, Philip L.
Publicado no Transl Res (2014)

Common Risk Alleles for Inflammatory Diseases Are Targets of Recent Positive Selection

Por Raj, Towfique, Kuchroo, Manik, Replogle, Joseph M., Raychaudhuri, Soumya, Stranger, Barbara E., De Jager, Philip L.
Publicado em 2013

Nucleosomes impede Cas9 access to DNA in vivo and in vitro

Por Horlbeck, Max A, Witkowsky, Lea B, Guglielmi, Benjamin, Replogle, Joseph M, Gilbert, Luke A, Villalta, Jacqueline E, Torigoe, Sharon E, Tjian, Robert, Weissman, Jonathan S
Publicado no eLife (2016)

Interindividual variation in human T regulatory cells

Por Ferraro, Alessandra, D’Alise, Anna Morena, Raj, Towfique, Asinovski, Natasha, Phillips, Roxanne, Ergun, Ayla, Replogle, Joseph M., Bernier, Angelina, Laffel, Lori, Stranger, Barbara E., De Jager, Philip L., Mathis, Diane, Benoist, Christophe
Publicado em 2014

CD33: increased inclusion of exon 2 implicates the Ig V-set domain in Alzheimer's disease susceptibility

Por Raj, Towfique, Ryan, Katie J., Replogle, Joseph M., Chibnik, Lori B., Rosenkrantz, Laura, Tang, Anna, Rothamel, Katie, Stranger, Barbara E., Bennett, David A., Evans, Denis A., De Jager, Philip L., Bradshaw, Elizabeth M.
Publicado em 2014

A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology

Por Replogle, Joseph M., Chan, Gail, White, Charles C., Raj, Towfique, Winn, Phoebe A., Evans, Denis A., Sperling, Reisa A., Chibnik, Lori B., Bradshaw, Elizabeth M., Schneider, Julie A., Bennett, David A., De Jager, Philip L.
Publicado no Ann Neurol (2015)

Modulation of TREM2 by CD33: a protein QTL study integrates Alzheimer loci in human monocytes

Por Chan, Gail, White, Charles C., Winn, Phoebe A., Cimpean, Maria, Replogle, Joseph M., Glick, Laura R., Cuerdon, Nicole E., Ryan, Katie J., Johnson, Keith A., Schneider, Julie A., Bennett, David A., Chibnik, Lori B., Sperling, Reisa A., Bradshaw, Elizabeth M., De Jager, Philip L.
Publicado no Nat Neurosci (2015)

Trans-pQTL study identifies immune crosstalk between Parkinson and Alzheimer loci

Por Chan, Gail, White, Charles C., Winn, Phoebe A., Cimpean, Maria, Replogle, Joseph M., Glick, Laura R., Cuerdon, Nicole E., Ryan, Katie J., Johnson, Keith A., Schneider, Julie A., Bennett, David A., Chibnik, Lori B., Sperling, Reisa A., De Jager, Philip L., Bradshaw, Elizabeth M.
Publicado no Neurol Genet (2016)

Genetic architecture of age-related cognitive decline in African Americans

Por Raj, Towfique, Chibnik, Lori B., McCabe, Cristin, Wong, Andus, Replogle, Joseph M., Yu, Lei, Gao, Sujuan, Unverzagt, Frederick W., Stranger, Barbara, Murrell, Jill, Barnes, Lisa, Hendrie, Hugh C., Foroud, Tatiana, Krichevsky, Anna, Bennett, David A., Hall, Kathleen S., Evans, Denis A., De Jager, Philip L.
Publicado no Neurol Genet (2016)

Rheumatoid arthritis-associated RBPJ polymorphism alters memory CD4(+) T cells

Por Orent, William, Mchenry, Allison R., Rao, Deepak A., White, Charles, Klein, Hans-Ulrich, Bassil, Ribal, Srivastava, Gyan, Replogle, Joseph M., Raj, Towfique, Frangieh, Michael, Cimpean, Maria, Cuerdon, Nicole, Chibnik, Lori, Khoury, Samia J., Karlson, Elizabeth W., Brenner, Michael B., De Jager, Philip, Bradshaw, Elizabeth M., Elyaman, Wassim
Publicado no Hum Mol Genet (2016)

Polarization of the Effects of Autoimmune and Neurodegenerative Risk Alleles in Leukocytes

Por Raj, Towfique, Rothamel, Katie, Mostafavi, Sara, Ye, Chun, Lee, Mark N., Replogle, Joseph M., Feng, Ting, Lee, Michelle, Asinovski, Natasha, Frohlich, Irene, Imboywa, Selina, Von Korff, Alina, Okada, Yukinori, Patsopoulos, Nikolaos A., Davis, Scott, McCabe, Cristin, Paik, Hyun-il, Srivastava, Gyan P., Raychaudhuri, Soumya, Hafler, David A., Koller, Daphne, Regev, Aviv, Hacohen, Nir, Mathis, Diane, Benoist, Christophe, Stranger, Barbara E., De Jager, Philip L.
Publicado no Science (2014)