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Trans-pQTL study identifies immune crosstalk between Parkinson and Alzheimer loci

OBJECTIVE: Given evidence from genetic studies, we hypothesized that there may be a shared component to the role of myeloid function in Parkinson and Alzheimer disease (PD and AD) and assessed whether PD susceptibility variants influenced protein expression of well-established AD-associated myeloid...

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Pubblicato in:Neurol Genet
Autori principali: Chan, Gail, White, Charles C., Winn, Phoebe A., Cimpean, Maria, Replogle, Joseph M., Glick, Laura R., Cuerdon, Nicole E., Ryan, Katie J., Johnson, Keith A., Schneider, Julie A., Bennett, David A., Chibnik, Lori B., Sperling, Reisa A., De Jager, Philip L., Bradshaw, Elizabeth M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wolters Kluwer 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962525/
https://ncbi.nlm.nih.gov/pubmed/27504496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXG.0000000000000090
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