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A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology

OBJECTIVE: Genome-wide association studies (GWAS) have linked variants in TREM2 and TREML2 with Alzheimer’s disease (AD) and AD endophenotypes. Here, we pursue a targeted analysis of the TREM locus in relation to cognitive decline and pathological features of AD. METHODS: Clinical, cognitive, and ne...

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Detalhes bibliográficos
Publicado no:Ann Neurol
Main Authors: Replogle, Joseph M., Chan, Gail, White, Charles C., Raj, Towfique, Winn, Phoebe A., Evans, Denis A., Sperling, Reisa A., Chibnik, Lori B., Bradshaw, Elizabeth M., Schneider, Julie A., Bennett, David A., De Jager, Philip L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461024/
https://ncbi.nlm.nih.gov/pubmed/25545807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24337
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