A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology

OBJECTIVE: Genome-wide association studies (GWAS) have linked variants in TREM2 and TREML2 with Alzheimer’s disease (AD) and AD endophenotypes. Here, we pursue a targeted analysis of the TREM locus in relation to cognitive decline and pathological features of AD. METHODS: Clinical, cognitive, and ne...

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Bibliografiske detaljer
Udgivet i:	Ann Neurol
Main Authors:	Replogle, Joseph M., Chan, Gail, White, Charles C., Raj, Towfique, Winn, Phoebe A., Evans, Denis A., Sperling, Reisa A., Chibnik, Lori B., Bradshaw, Elizabeth M., Schneider, Julie A., Bennett, David A., De Jager, Philip L.
Format:	Artigo
Sprog:	Inglês
Udgivet:	2015
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4461024/ https://ncbi.nlm.nih.gov/pubmed/25545807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24337
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A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology

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