Polarization of the Effects of Autoimmune and Neurodegenerative Risk Alleles in Leukocytes

To extend our understanding of the genetic basis of human immune function and dysfunction, we performed an expression quantitative trait locus (eQTL) study of purified CD4(+) T cells and monocytes, representing adaptive and innate immunity, in a multi-ethnic cohort of 461 healthy individuals. Contex...

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Detaylı Bibliyografya
Yayımlandı:Science
Asıl Yazarlar: Raj, Towfique, Rothamel, Katie, Mostafavi, Sara, Ye, Chun, Lee, Mark N., Replogle, Joseph M., Feng, Ting, Lee, Michelle, Asinovski, Natasha, Frohlich, Irene, Imboywa, Selina, Von Korff, Alina, Okada, Yukinori, Patsopoulos, Nikolaos A., Davis, Scott, McCabe, Cristin, Paik, Hyun-il, Srivastava, Gyan P., Raychaudhuri, Soumya, Hafler, David A., Koller, Daphne, Regev, Aviv, Hacohen, Nir, Mathis, Diane, Benoist, Christophe, Stranger, Barbara E., De Jager, Philip L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910825/
https://ncbi.nlm.nih.gov/pubmed/24786080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1249547
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