Isocitrate Dehydrogenase 1 and 2 Mutations in Cancer: Alterations at a Crossroads of Cellular Metabolism

door Reitman, Zachary J., Yan, Hai
Gepubliceerd in 2010

Promoting a new brain tumor mutation: TERT promoter mutations in CNS tumors

door Reitman, Zachary J., Pirozzi, Christopher J., Yan, Hai
Gepubliceerd in 2013

Releasing the Block: Setting Differentiation Free with Mutant IDH Inhibitors

door Pirozzi, Christopher J., Reitman, Zachary J., Yan, Hai
Gepubliceerd in Cancer Cell (2013)

IDH1 and IDH2: Not Your Typical Oncogenes

door Reitman, Zachary J., Parsons, D. Williams, Yan, Hai
Gepubliceerd in Cancer Cell (2010)

Genetic dissection of leukemia-associated IDH1 and IDH2 mutants and D-2-hydroxyglutarate in Drosophila

door Reitman, Zachary J., Sinenko, Sergey A., Spana, Eric P., Yan, Hai
Gepubliceerd in Blood (2015)

Relationship Between Time of First Publication and Subsequent Publication Success Among Non-PhD Physician-Scientists

door Riggs, Kevin R., Reitman, Zachary J., Mielenz, Thelma J., Goodman, Philip C.
Gepubliceerd in 2012

Radiolabeled inhibitors as probes for imaging mutant IDH1 expression in gliomas: synthesis and preliminary evaluation of labeled butyl-phenyl sulfonamide analogs

door Chitneni, Satish K., Reitman, Zachary J., Gooden, David M., Yan, Hai, Zalutsky, Michael R.
Gepubliceerd in Eur J Med Chem (2016)

Enzyme Redesign Guided by Cancer-Derived IDH1 Mutations

door Reitman, Zachary J., Choi, Bryan D., Spasojevic, Ivan, Bigner, Darell D., Sampson, John H., Yan, Hai
Gepubliceerd in 2012

Synthesis and evaluation of radiolabeled AGI-5198 analogues as candidate radiotracers for imaging mutant IDH1 expression in tumors

door Chitneni, Satish K., Reitman, Zachary J., Spicehandler, Rebecca, Gooden, David M., Yan, Hai, Zalutsky, Michael R.
Gepubliceerd in Bioorg Med Chem Lett (2018)

Picornavirus genome replication: Identification of the surface of the poliovirus (PV) 3C dimer that interacts with PV 3Dpol during VPg uridylylation and construction of a structura...

door Shen, Miaoqing, Reitman, Zachary J., Zhao, Yan, Moustafa, Ibrahim, Wang, Qixin, Arnold, Jamie J., Pathak, Harsh B., Cameron, Craig E.
Gepubliceerd in 2007

2-Hydroxyglutarate Production, but Not Dominant Negative Function, Is Conferred by Glioma-Derived NADP(+)-Dependent Isocitrate Dehydrogenase Mutations

door Jin, Genglin, Reitman, Zachary J., Spasojevic, Ivan, Batinic-Haberle, Ines, Yang, Jian, Schmidt-Kittler, Oleg, Bigner, Darell D., Yan, Hai
Gepubliceerd in 2011

IDH1 mutation identified in human melanoma

door Lopez, Giselle Y., Reitman, Zachary J., Solomon, David, Waldman, Todd, Bigner, Darell D., McLendon, Roger E., Samuels, Yardena, Yan, Hai
Gepubliceerd in 2010

IDH1 and IDH2 hotspot mutations are not found in canine glioma

door Reitman, Zachary J., Olby, Natasha J., Mariani, Christopher L., Thomas, Rachael, Breen, Matthew, Bigner, Darrell D., McLendon, Roger E., Yan, Hai
Gepubliceerd in 2010

Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome

door Reitman, Zachary J., Jin, Genglin, Karoly, Edward D., Spasojevic, Ivan, Yang, Jian, Kinzler, Kenneth W., He, Yiping, Bigner, Darell D., Vogelstein, Bert, Yan, Hai
Gepubliceerd in 2011

Cancer-associated Isocitrate Dehydrogenase 1 (IDH1) R132H Mutation and d-2-Hydroxyglutarate Stimulate Glutamine Metabolism under Hypoxia

door Reitman, Zachary J., Duncan, Christopher G., Poteet, Ethan, Winters, Ali, Yan, Liang-Jun, Gooden, David M., Spasojevic, Ivan, Boros, Laszlo G., Yang, Shao-Hua, Yan, Hai
Gepubliceerd in 2014

Disruption of wild type IDH1 suppresses D-2-hydroxyglutarate production in IDH1-mutated gliomas

door Jin, Genglin, Reitman, Zachary J., Duncan, Chritopher G., Spasojevic, Ivan, Gooden, David M., Rasheed, B. Ahmed, Yang, Rui, Lopez, Giselle Y., He, Yiping, McLendon, Roger E., Bigner, Darell D., Yan, Hai
Gepubliceerd in 2012

The genetic landscape of anaplastic astrocytoma

door Killela, Patrick J., Pirozzi, Christopher J., Reitman, Zachary J., Jones, Sian, Rasheed, B. Ahmed, Lipp, Eric, Friedman, Henry, Friedman, Allan H., He, Yiping, McLendon, Roger E., Bigner, Darell D., Yan, Hai
Gepubliceerd in 2013

DIPG-12. CHARACTERIZING THE ROLE OF PPM1D MUTATIONS IN THE PATHOGENESIS OF DIFFUSE INTRINSIC PONTINE GLIOMAS (DIPGs)

door Khadka, Prasidda, Reitman, Zachary J, Buchan, Graham, Hartley, Rachel, Bear, Heather, Georgis, Yohanna, Jarmale, Spandana, Schoolcraft, Kathleen, Miller, Peter, Stiles, Charles D, Chowdhury, Dipanjan, Haas-Kogan, Daphne, Johannessen, Cory, Ebert, Benjamin L, Ligon, Keith L, Phoenix, Timothy, Beroukhim, Rameen, Bandopadhayay, Pratiti
Gepubliceerd in Neuro Oncol (2019)

The genome-wide mutational landscape of pituitary adenomas

door Song, Zhi-Jian, Reitman, Zachary J, Ma, Zeng-Yi, Chen, Jian-Hua, Zhang, Qi-Lin, Shou, Xue-Fei, Huang, Chuan-Xin, Wang, Yong-Fei, Li, Shi-Qi, Mao, Ying, Zhou, Liang-Fu, Lian, Bao-Feng, Yan, Hai, Shi, Yong-Yong, Zhao, Yao
Gepubliceerd in Cell Res (2016)

Exomic Sequencing of Four Rare Central Nervous System Tumor Types

door Bettegowda, Chetan, Agrawal, Nishant, Jiao, Yuchen, Wang, Yuxuan, Wood, Laura D., Rodriguez, Fausto J., Hruban, Ralph H., Gallia, Gary L., Binder, Zev A., Riggins, Callen J., Salmasi, Vafi, Riggins, Gregory J., Reitman, Zachary J., Rasheed, Ahmed, Keir, Stephen, Shinjo, Sueli, Marie, Suely, McLendon, Roger, Jallo, George, Vogelstein, Bert, Bigner, Darell, Yan, Hai, Kinzler, Kenneth W., Papadopoulos, Nickolas
Gepubliceerd in 2013