Isocitrate Dehydrogenase 1 and 2 Mutations in Cancer: Alterations at a Crossroads of Cellular Metabolism

par Reitman, Zachary J., Yan, Hai
Publié 2010

Promoting a new brain tumor mutation: TERT promoter mutations in CNS tumors

par Reitman, Zachary J., Pirozzi, Christopher J., Yan, Hai
Publié 2013

Releasing the Block: Setting Differentiation Free with Mutant IDH Inhibitors

par Pirozzi, Christopher J., Reitman, Zachary J., Yan, Hai
Publié dans Cancer Cell (2013)

IDH1 and IDH2: Not Your Typical Oncogenes

par Reitman, Zachary J., Parsons, D. Williams, Yan, Hai
Publié dans Cancer Cell (2010)

Genetic dissection of leukemia-associated IDH1 and IDH2 mutants and D-2-hydroxyglutarate in Drosophila

par Reitman, Zachary J., Sinenko, Sergey A., Spana, Eric P., Yan, Hai
Publié dans Blood (2015)

Relationship Between Time of First Publication and Subsequent Publication Success Among Non-PhD Physician-Scientists

par Riggs, Kevin R., Reitman, Zachary J., Mielenz, Thelma J., Goodman, Philip C.
Publié 2012

Radiolabeled inhibitors as probes for imaging mutant IDH1 expression in gliomas: synthesis and preliminary evaluation of labeled butyl-phenyl sulfonamide analogs

par Chitneni, Satish K., Reitman, Zachary J., Gooden, David M., Yan, Hai, Zalutsky, Michael R.
Publié dans Eur J Med Chem (2016)

Enzyme Redesign Guided by Cancer-Derived IDH1 Mutations

par Reitman, Zachary J., Choi, Bryan D., Spasojevic, Ivan, Bigner, Darell D., Sampson, John H., Yan, Hai
Publié 2012

Synthesis and evaluation of radiolabeled AGI-5198 analogues as candidate radiotracers for imaging mutant IDH1 expression in tumors

par Chitneni, Satish K., Reitman, Zachary J., Spicehandler, Rebecca, Gooden, David M., Yan, Hai, Zalutsky, Michael R.
Publié dans Bioorg Med Chem Lett (2018)

Picornavirus genome replication: Identification of the surface of the poliovirus (PV) 3C dimer that interacts with PV 3Dpol during VPg uridylylation and construction of a structura...

par Shen, Miaoqing, Reitman, Zachary J., Zhao, Yan, Moustafa, Ibrahim, Wang, Qixin, Arnold, Jamie J., Pathak, Harsh B., Cameron, Craig E.
Publié 2007

2-Hydroxyglutarate Production, but Not Dominant Negative Function, Is Conferred by Glioma-Derived NADP(+)-Dependent Isocitrate Dehydrogenase Mutations

par Jin, Genglin, Reitman, Zachary J., Spasojevic, Ivan, Batinic-Haberle, Ines, Yang, Jian, Schmidt-Kittler, Oleg, Bigner, Darell D., Yan, Hai
Publié 2011

IDH1 mutation identified in human melanoma

par Lopez, Giselle Y., Reitman, Zachary J., Solomon, David, Waldman, Todd, Bigner, Darell D., McLendon, Roger E., Samuels, Yardena, Yan, Hai
Publié 2010

IDH1 and IDH2 hotspot mutations are not found in canine glioma

par Reitman, Zachary J., Olby, Natasha J., Mariani, Christopher L., Thomas, Rachael, Breen, Matthew, Bigner, Darrell D., McLendon, Roger E., Yan, Hai
Publié 2010

Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome

par Reitman, Zachary J., Jin, Genglin, Karoly, Edward D., Spasojevic, Ivan, Yang, Jian, Kinzler, Kenneth W., He, Yiping, Bigner, Darell D., Vogelstein, Bert, Yan, Hai
Publié 2011

Cancer-associated Isocitrate Dehydrogenase 1 (IDH1) R132H Mutation and d-2-Hydroxyglutarate Stimulate Glutamine Metabolism under Hypoxia

par Reitman, Zachary J., Duncan, Christopher G., Poteet, Ethan, Winters, Ali, Yan, Liang-Jun, Gooden, David M., Spasojevic, Ivan, Boros, Laszlo G., Yang, Shao-Hua, Yan, Hai
Publié 2014

Disruption of wild type IDH1 suppresses D-2-hydroxyglutarate production in IDH1-mutated gliomas

par Jin, Genglin, Reitman, Zachary J., Duncan, Chritopher G., Spasojevic, Ivan, Gooden, David M., Rasheed, B. Ahmed, Yang, Rui, Lopez, Giselle Y., He, Yiping, McLendon, Roger E., Bigner, Darell D., Yan, Hai
Publié 2012

The genetic landscape of anaplastic astrocytoma

par Killela, Patrick J., Pirozzi, Christopher J., Reitman, Zachary J., Jones, Sian, Rasheed, B. Ahmed, Lipp, Eric, Friedman, Henry, Friedman, Allan H., He, Yiping, McLendon, Roger E., Bigner, Darell D., Yan, Hai
Publié 2013

DIPG-12. CHARACTERIZING THE ROLE OF PPM1D MUTATIONS IN THE PATHOGENESIS OF DIFFUSE INTRINSIC PONTINE GLIOMAS (DIPGs)

par Khadka, Prasidda, Reitman, Zachary J, Buchan, Graham, Hartley, Rachel, Bear, Heather, Georgis, Yohanna, Jarmale, Spandana, Schoolcraft, Kathleen, Miller, Peter, Stiles, Charles D, Chowdhury, Dipanjan, Haas-Kogan, Daphne, Johannessen, Cory, Ebert, Benjamin L, Ligon, Keith L, Phoenix, Timothy, Beroukhim, Rameen, Bandopadhayay, Pratiti
Publié dans Neuro Oncol (2019)

The genome-wide mutational landscape of pituitary adenomas

par Song, Zhi-Jian, Reitman, Zachary J, Ma, Zeng-Yi, Chen, Jian-Hua, Zhang, Qi-Lin, Shou, Xue-Fei, Huang, Chuan-Xin, Wang, Yong-Fei, Li, Shi-Qi, Mao, Ying, Zhou, Liang-Fu, Lian, Bao-Feng, Yan, Hai, Shi, Yong-Yong, Zhao, Yao
Publié dans Cell Res (2016)

Exomic Sequencing of Four Rare Central Nervous System Tumor Types

par Bettegowda, Chetan, Agrawal, Nishant, Jiao, Yuchen, Wang, Yuxuan, Wood, Laura D., Rodriguez, Fausto J., Hruban, Ralph H., Gallia, Gary L., Binder, Zev A., Riggins, Callen J., Salmasi, Vafi, Riggins, Gregory J., Reitman, Zachary J., Rasheed, Ahmed, Keir, Stephen, Shinjo, Sueli, Marie, Suely, McLendon, Roger, Jallo, George, Vogelstein, Bert, Bigner, Darell, Yan, Hai, Kinzler, Kenneth W., Papadopoulos, Nickolas
Publié 2013