The role of TIM-containing molecules in airway disease and their potential as therapeutic targets

Por Vega-Carrascal, Isabel, Reeves, Emer P, McElvaney, Noel G
Publicado em 2012

Reassessment of the microbicidal activity of reactive oxygen species and hypochlorous acid with reference to the phagocytic vacuole of the neutrophil granulocyte

Por Reeves, Emer P., Nagl, Markus, Godovac-Zimmermann, Jasminca, Segal, Anthony W.
Publicado em 2003

Hypertonic Saline in Treatment of Pulmonary Disease in Cystic Fibrosis

Por Reeves, Emer P., Molloy, Kevin, Pohl, Kerstin, McElvaney, Noel G.
Publicado em 2012

Superoxide Production in Galleria mellonella Hemocytes: Identification of Proteins Homologous to the NADPH Oxidase Complex of Human Neutrophils

Por Bergin, David, Reeves, Emer P., Renwick, Julie, Wientjes, Frans B., Kavanagh, Kevin
Publicado em 2005

The Involvement of Glycosaminoglycans in Airway Disease Associated with Cystic Fibrosis

Por Reeves, Emer P., Bergin, David A., Murray, Michelle A., McElvaney, Noel G.
Publicado no ScientificWorldJournal (2011)

The Human Cathelicidin Antimicrobial Peptide LL-37 Promotes the Growth of the Pulmonary Pathogen Aspergillus fumigatus

Por Sheehan, Gerard, Bergsson, Gudmundur, McElvaney, Noel G., Reeves, Emer P., Kavanagh, Kevin
Publicado no Infect Immun (2018)

Animal Models of Cystic Fibrosis Pathology: Phenotypic Parallels and Divergences

Por Lavelle, Gillian M., White, Michelle M., Browne, Niall, McElvaney, Noel G., Reeves, Emer P.
Publicado no Biomed Res Int (2016)

The impact of alpha-1 antitrypsin augmentation therapy on neutrophil-driven respiratory disease in deficient individuals

Por Dunlea, Danielle M, Fee, Laura T, McEnery, Thomas, McElvaney, Noel G, Reeves, Emer P
Publicado no J Inflamm Res (2018)

Airway inflammatory markers in individuals with cystic fibrosis and non-cystic fibrosis bronchiectasis

Por Bergin, David A, Hurley, Killian, Mehta, Adwait, Cox, Stephen, Ryan, Dorothy, O’Neill, Shane J, Reeves, Emer P, McElvaney, Noel G
Publicado em 2013

Inhaled hypertonic saline for cystic fibrosis: Reviewing the potential evidence for modulation of neutrophil signalling and function

Por Reeves, Emer P, McCarthy, Cormac, McElvaney, Oliver J, Vijayan, Maya Sakthi N, White, Michelle M, Dunlea, Danielle M, Pohl, Kerstin, Lacey, Noreen, McElvaney, Noel G
Publicado no World J Crit Care Med (2015)

Galectin-9 Signaling through TIM-3 Is Involved in Neutrophil-Mediated Gram-Negative Bacterial Killing: An Effect Abrogated within the Cystic Fibrosis Lung

Por Vega-Carrascal, Isabel, Bergin, David A., McElvaney, Oliver J., McCarthy, Cormac, Banville, Nessa, Pohl, Kerstin, Hirashima, Mitsuomi, Kuchroo, Vijay K., Reeves, Emer P., McElvaney, Noel G.
Publicado no J Immunol (2014)

α-1 Antitrypsin regulates human neutrophil chemotaxis induced by soluble immune complexes and IL-8

Por Bergin, David A., Reeves, Emer P., Meleady, Paula, Henry, Michael, McElvaney, Oliver J., Carroll, Tomás P., Condron, Claire, Chotirmall, Sanjay H., Clynes, Martin, O’Neill, Shane J., McElvaney, Noel G.
Publicado em 2010

Granzyme B-dependent proteolysis acts as a switch to enhance the pro-inflammatory activity of IL-1α

Por Afonina, Inna S., Tynan, Graham A., Logue, Susan E., Cullen, Sean P., Bots, Michael, Lüthi, Alexander U., Reeves, Emer P., McElvaney, Noel G., Medema, Jan P., Lavelle, Ed C., Martin, Seamus J.
Publicado em 2011

A neutrophil intrinsic impairment affecting Rab27a and degranulation in cystic fibrosis is corrected by CFTR potentiator therapy

Por Pohl, Kerstin, Hayes, Elaine, Keenan, Joanne, Henry, Michael, Meleady, Paula, Molloy, Kevin, Jundi, Bakr, Bergin, David A., McCarthy, Cormac, McElvaney, Oliver J., White, Michelle M., Clynes, Martin, Reeves, Emer P., McElvaney, Noel G.
Publicado em 2014

Neutrophil Membrane Cholesterol Content is a Key Factor in Cystic Fibrosis Lung Disease

Por White, Michelle M., Geraghty, Patrick, Hayes, Elaine, Cox, Stephen, Leitch, William, Alfawaz, Bader, Lavelle, Gillian M., McElvaney, Oliver J., Flannery, Ryan, Keenan, Joanne, Meleady, Paula, Henry, Michael, Clynes, Martin, Gunaratnam, Cedric, McElvaney, Noel G., Reeves, Emer P.
Publicado no EBioMedicine (2017)

Intracellular Secretory Leukoprotease Inhibitor Modulates Inositol 1,4,5-Triphosphate Generation and Exerts an Anti-Inflammatory Effect on Neutrophils of Individuals with Cystic Fi...

Por Reeves, Emer P., Banville, Nessa, Ryan, Dorothy M., O'Reilly, Niamh, Bergin, David A., Pohl, Kerstin, Molloy, Kevin, McElvaney, Oliver J., Alsaleh, Khalifah, Aljorfi, Ahmed, Kandalaft, Osama, O'Flynn, Eimear, Geraghty, Patrick, O'Neill, Shane J., McElvaney, Noel G.
Publicado em 2013

5 Year Expression and Neutrophil Defect Repair after Gene Therapy in Alpha-1 Antitrypsin Deficiency

Por Mueller, Christian, Gernoux, Gwladys, Gruntman, Alisha M., Borel, Florie, Reeves, Emer P., Calcedo, Roberto, Rouhani, Farshid N., Yachnis, Anthony, Humphries, Margaret, Campbell-Thompson, Martha, Messina, Louis, Chulay, Jeffrey D., Trapnell, Bruce, Wilson, James M., McElvaney, Noel G., Flotte, Terence R.
Publicado no Mol Ther (2017)