Neutrophil Membrane Cholesterol Content is a Key Factor in Cystic Fibrosis Lung Disease

BACKGROUND: Identification of mechanisms promoting neutrophil trafficking to the lungs of patients with cystic fibrosis (CF) is a challenge for next generation therapeutics. Cholesterol, a structural component of neutrophil plasma membranes influences cell adhesion, a key step in transmigration. The...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: White, Michelle M., Geraghty, Patrick, Hayes, Elaine, Cox, Stephen, Leitch, William, Alfawaz, Bader, Lavelle, Gillian M., McElvaney, Oliver J., Flannery, Ryan, Keenan, Joanne, Meleady, Paula, Henry, Michael, Clynes, Martin, Gunaratnam, Cedric, McElvaney, Noel G., Reeves, Emer P.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605378/
https://ncbi.nlm.nih.gov/pubmed/28835336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.08.013
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