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Animal Models of Cystic Fibrosis Pathology: Phenotypic Parallels and Divergences
Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The resultant characteristic ion transport defect results in decreased mucociliary clearance, bacterial colonisation, and chronic neutrophil-dominated inflammation. Much knowledge surr...
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| Publicado no: | Biomed Res Int |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4908263/ https://ncbi.nlm.nih.gov/pubmed/27340661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/5258727 |
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