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Animal Models of Cystic Fibrosis Pathology: Phenotypic Parallels and Divergences
Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The resultant characteristic ion transport defect results in decreased mucociliary clearance, bacterial colonisation, and chronic neutrophil-dominated inflammation. Much knowledge surr...
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| 出版年: | Biomed Res Int |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Hindawi Publishing Corporation
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4908263/ https://ncbi.nlm.nih.gov/pubmed/27340661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/5258727 |
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