The impact of alpha-1 antitrypsin augmentation therapy on neutrophil-driven respiratory disease in deficient individuals

Alpha-1 antitrypsin (AAT) is the most abundant serine protease inhibitor circulating in the blood. AAT deficiency (AATD) is an autosomal codominant condition affecting an estimated 3.4 million individuals worldwide. The clinical disease associated with AATD can present in a number of ways including...

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Vydáno v:J Inflamm Res
Hlavní autoři: Dunlea, Danielle M, Fee, Laura T, McEnery, Thomas, McElvaney, Noel G, Reeves, Emer P
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2018
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5875399/
https://ncbi.nlm.nih.gov/pubmed/29618937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JIR.S156405
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