Galectin-9 Signaling through TIM-3 Is Involved in Neutrophil-Mediated Gram-Negative Bacterial Killing: An Effect Abrogated within the Cystic Fibrosis Lung

The T cell Ig and mucin domain–containing molecule (TIM) family of receptors have emerged as potential therapeutic targets to correct abnormal immune function in chronic inflammatory conditions. TIM-3 serves as a functional receptor in structural cells of the airways and via the ligand galectin-9 (G...

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Bibliographic Details
Published in:J Immunol
Main Authors: Vega-Carrascal, Isabel, Bergin, David A., McElvaney, Oliver J., McCarthy, Cormac, Banville, Nessa, Pohl, Kerstin, Hirashima, Mitsuomi, Kuchroo, Vijay K., Reeves, Emer P., McElvaney, Noel G.
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997615/
https://ncbi.nlm.nih.gov/pubmed/24477913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300711
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