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Galectin-9 binding to Tim-3 renders activated human CD4(+) T cells less susceptible to HIV-1 infection
Galectin-9 (Gal-9) is a tandem repeat-type member of the galectin family and is a ligand for T-cell immunoglobulin mucin domain 3 (Tim-3), a type-I glycoprotein that is persistently expressed on dysfunctional T cells during chronic infection. Studies in autoimmune diseases and chronic viral infectio...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Hematology
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3359739/ https://ncbi.nlm.nih.gov/pubmed/22438246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-11-389585 |
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