Galectin-9 prolongs the survival of septic mice by expanding tim-3-expressing natural killer T cells and PDCA-1(+) CD11c(+) macrophages

INTRODUCTION: Galectin-9 ameliorates various inflammatory conditions including autoimmune diseases by regulating T cell and macrophage/dendritic cell (DC) functions. However, the effect of galectin-9 on polymicrobial sepsis has not been assessed. METHODS: We induced polymicrobial sepsis by cecal lig...

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Autors principals: Kadowaki, Takashi, Morishita, Asahiro, Niki, Toshiro, Hara, Junko, Sato, Miwa, Tani, Joji, Miyoshi, Hisaaki, Yoneyama, Hirohito, Masaki, Tsutomu, Hattori, Toshio, Matsukawa, Akihiro, Hirashima, Mitsuomi
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4056346/
https://ncbi.nlm.nih.gov/pubmed/24321251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc13147
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