Cell Surface Galectin-9 Expressing Th Cells Regulate Th17 and Foxp3(+) Treg Development by Galectin-9 Secretion

Galectin-9 (Gal-9), a β-galactoside binding mammalian lectin, regulates immune responses by reducing pro-inflammatory IL-17-producing Th cells (Th17) and increasing anti-inflammatory Foxp3(+) regulatory T cells (Treg) in vitro and in vivo. These functions of Gal-9 are thought to be exerted by bindin...

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Autors principals: Oomizu, Souichi, Arikawa, Tomohiro, Niki, Toshiro, Kadowaki, Takeshi, Ueno, Masaki, Nishi, Nozomu, Yamauchi, Akira, Hattori, Toshio, Masaki, Tsutomu, Hirashima, Mitsuomi
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492452/
https://ncbi.nlm.nih.gov/pubmed/23144904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048574
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