Treg-mediated Suppression of Inflammation Induced by DR3 Signaling is Dependent on Galectin-9

Stimulation of several TNF receptor family proteins has been shown to dampen inflammatory disease in murine models through augmenting the number and/or activity of regulatory T cells (Treg). We recently found that one molecule, 4-1BB, utilized binding to Galectin-9 to exert its immunosuppressive eff...

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Udgivet i:J Immunol
Main Authors: Madireddi, Shravan, Eun, So-Young, Mehta, Amit K., Birta, Aruna, Zajonc, Dirk M, Niki, Toshiro, Hirashima, Mitsuomi, Podack, Eckhard R., Schreiber, Taylor H., Croft, Michael
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659314/
https://ncbi.nlm.nih.gov/pubmed/28877989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700575
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