Galectin-9 Ameliorates Clinical Severity of MRL/lpr Lupus-Prone Mice by Inducing Plasma Cell Apoptosis Independently of Tim-3

Galectin-9 ameliorates various murine autoimmune disease models by regulating T cells and macrophages, although it is not known what role it may have in B cells. The present experiment shows that galectin-9 ameliorates a variety of clinical symptoms, such as proteinuria, arthritis, and hematocrit in...

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Detalhes bibliográficos
Main Authors: Moritoki, Masahiro, Kadowaki, Takeshi, Niki, Toshiro, Nakano, Daisuke, Soma, Genichiro, Mori, Hirohito, Kobara, Hideki, Masaki, Tsutomu, Kohno, Masakazu, Hirashima, Mitsuomi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621869/
https://ncbi.nlm.nih.gov/pubmed/23585851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060807
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