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Oestrogen is a potent disease accelerator in SLE-prone MRL lpr/lpr mice.

The influence of oestrogen on the lupus disease in MRL/l mice has been investigated. Adult, castrated male and female MRL/l mice were administered with s.c. injections of 3.2 micrograms of 17 beta-oestradiol twice a week. The results clearly demonstrate that a relatively small dose of oestrogen is a...

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Main Authors: Carlsten, H, Tarkowski, A, Holmdahl, R, Nilsson, L A
格式: Artigo
語言:Inglês
出版: 1990
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1535196/
https://ncbi.nlm.nih.gov/pubmed/2372993
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