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Depression is an Early Disease Manifestation in Lupus-Prone MRL/lpr Mice

Many lupus patients develop neuropsychiatric manifestations, including cognitive dysfunction, depression, and anxiety. However, it is not clear if neuropsychiatric lupus is a primary disease manifestation, or is secondary to non-CNS disease. We found that MRL/lpr lupus-prone mice exhibited significa...

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Bibliographic Details
Main Authors: Gao, Hua-Xin, Campbell, Sean R., Cui, Min-Hui, Zong, Pu, Hwang, Jong hee, Gulinello, Maria, Putterman, Chaim
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675630/
https://ncbi.nlm.nih.gov/pubmed/19121871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2008.11.009
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