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The new complement inhibitor CRIg/FH ameliorates lupus nephritis in lupus-prone MRL/lpr mice

Abstract Backgrounds The aberrant activation of complement system is critically involved in lupus nephropathy. Recent study showed complement C3 inhibitor was effective in the treatment of lupus nephropathy. In this study, we investigate the effect of a novel complement C3 inhibitor, CRIg/FH, in the...

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Detalhes bibliográficos
Main Authors: Yu Shi, Wen Yao, Li Sun, Guomin Li, Haimei Liu, Peipei Ding, Weiguo Hu, Hong Xu
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-11-01
Colecção:BMC Nephrology
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Acesso em linha:http://link.springer.com/article/10.1186/s12882-019-1599-0
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